Immune Disorders Of The Skin

Question 1

Psoriasis: chronic ______ disease of the skin characterized by _______ plaques covered with ______ _____

Answer 1

Autoimmune
Erythematous
Silvery scale

Question 2

Psoriasis:

Common on what 5 parts?

Answer 2

Ears, scalp, knees, elbows, genitals

Question 3

Psoriasis:

Common complaints: _____ and ____ from dry cracked lesions

Answer 3

Itching and pain

Question 4

Psoriasis:

______ course: exacerbations and remission, common

Answer 4

Variable

Question 5

Psoriasis:

May be associated with _________ arthritis, joint pain (particularly of ____, ____ joints

Answer 5

Psoriatic

Small, distal

Question 6

Psoriasis: Etiology:

_______, associated with _____ disorders, certain ______

Answer 6

Hereditary
Immune
Drugs

Question 7

Psoriasis:
Precipitating factors:
Name 8

Answer 7

Trauma
Infection
Pregnancy
Endocrine changes
Smoking
Stress
Anxiety
Cold weather

Question 8

Psoriasis: management:
Is there a cure?
_____ preparations (corticosteroids, occlusive ointments, _____ tar)
_________ drugs (methotrexate)

What other condition is methotrexate used for?

Answer 8

Topical — coal tar
Immunosuppressant drugs

RA

Question 9

Psoriasis:
PT interventions:
1. Long wave ______ light
2. Combination ___ light with ______ _______ ______ (psoralens)

Answer 9

UV

UV - with oral photosensitizing drugs

Question 10

Lupus Erythematosus: what are the two types?

Answer 10

Discoid LE (DLE) and Systemic LE (SLE)

Question 11

Lupus Erythematosus: chronic, _______ _________ inflammatory disorder or _____ ______

Answer 11

PROGRESSIVE
Autoimmune
CT

Question 12

Lupus Erythematosus: characteristic _____ _____ with raised, red scaly plaques

Answer 12

Red rash

Question 13

Lupus Erythematosus: DLE:
Only affects the \_\_\_\_\_\_
Flare ups with \_\_\_ exposure
Lesions can resolve or cause \_\_\_\_\_\_
Permanent \_\_\_\_\_, hypo\_\_\_\_\_\_\_\_, or hyper\_\_\_\_\_\_\_\_

Answer 13

SKIN
Sun
Atrophy
Scarring
Hypo or hyper pigmentation

Question 14

Lupus Erythematosus: SLE: Chronic ________ inflammatory disorder affecting multiple ______ systems

Answer 14

Systemic

Organ

Question 15

Lupus Erythematosus: SLE: includes what 6 systems?

Answer 15

Skin
Joints
Kidneys
Heart
Nervous system
Mucous membranes

Question 16

Lupus Erythematosus: SLE: Can be ______

Answer 16

Fatal

Question 17

Lupus Erythematosus: SLE: commonly affects what age/gender?

Answer 17

YOUNG WOMEN

Question 18

Lupus Erythematosus: SLE: Symptoms can include \_\_\_\_\_, \_\_\_\_\_\_,
Characteristic \_\_\_\_\_\_\_ rash across bridge of nose
Skin \_\_\_\_\_
Chronic \_\_\_\_\_
Arthralgia
Arthritis
Skin \_\_\_\_\_\_
Photosensitivity
Anemia
Hair \_\_\_\_\_\_\_
\_\_\_\_\_\_ phenomenon

Answer 18

Fever, malaise
Butterfly
Lesions
Fatigue
Rashes
Loss
Raynauds

Question 19

Lupus Erythematosus: Management?

Is there a cure?

Answer 19

NO CURE

Question 20

Lupus Erythematosus: Management:
______ treatment of skin lesions (corticosteroid creams)
Salicylates or indomethacin with ______ and _____ pain
Immunosuppressive agents (cytotoxic agents) with _____ ______ disease

Answer 20

Topical
Fever and joint pain
Life threatening

Question 21

Lupus Erythematosus: Observe for side effects of _________: edema, wt gain, acne, HYPERTENSION, bruising, purplish stretch marks

Answer 21

Corticosteroids

Question 22

Lupus Erythematosus: Long term use of corticosteroids is associated with increased susceptibility to _________ (immunosuppresed pt); __________, myopathy, ______ rupture, _______, gastric irritation, low ________

Answer 22

Infection
Osteoporosis
Tendon rupture
Diabetes
Low potassium

Low potassium = hypokalemia = flat T, prolonged PR and QT. Arrhythmias may progress to VFib

Question 23

Systemic Sclerosis (Scleroderma): Chronic _________ diffuse disease of ______ ______ causing fibrosis of skin, joints, blood vessels, and internal organs (GI tract, lungs, heart, kidneys)

Usually accompanied by ________ phenomenon

Answer 23

Autoimmune
Connective tissue

Raynauds

Question 24

Systemic Sclerosis (Scleroderma):
Skin is \_\_\_\_, \_\_\_\_, edematous, firmly bound to subcutaneous tissue

Answer 24

Firm, taut

Question 25

``` Systemic Sclerosis (Scleroderma): Limited Systemic Sclerosis: ______ skin involvement of ____ extremities and ______ ```

Answer 25

Symmetrical Distal Face

Question 26

``` Systemic Sclerosis (Scleroderma): Limited Systemic Sclerosis: Slow progression of _____ changes Late ______ and ________ hypertension involvement ```

Answer 26

Skin | Visceral and pulmonary

Question 27

``` Systemic Sclerosis (Scleroderma): Limited Systemic Sclerosis: Associated with _____ syndrome? What does it stand for? ```

Answer 27

``` CREST C: Calcinosis R: Raynauds E: Esophageal dysfunction S: Sclerodactyly (localized thickening/tightness of skin over fingers and toes) T: Telangiectasias (spider veins) ```

Question 28

Systemic Sclerosis: Diffuse Systemic Scleroderma: _______ widespread skin involvement of _____ and ____ extremities, face, trunk

Answer 28

Symmetrical | Distal and proximal

Question 29

Systemic Sclerosis: Diffuse Systemic Scleroderma: | _____ progression of skin changes with early _____ involvement

Answer 29

Rapid | Visceral

Question 30

Systemic Sclerosis: Diffuse Systemic Scleroderma: | Important internal organs that are frequently involved include what 3?

Answer 30

Kidneys, heart, lung

Question 31

Systemic Sclerosis: Management: __ specific therapy Supportive therapy can include what 4 things?

Answer 31

``` NO Corticosteroids Vasodilators Analgesics Immunosuppressive agents ```

Question 32

Systemic Sclerosis: PT slows development of ______ and ______

Answer 32

Contracture and deformity

Question 33

Systemic Sclerosis: Precautions with ________ skin Sensitive to ________ Acute _____ may occur Stress regular ____ checks and _____ monitoring Pulm htn can lead to ____ sided HF in severe cases

Answer 33

``` Sclerosed Pressure Htn BP and VS RIGHT ```

Question 34

Polymyositis (PM): | ____ disease characterized by _____, _____, and ______ of muscles

Answer 34

CT | Edema, inflamm, and degeneration

Question 35

Polymyositis (PM): | _______ is associated with some forms

Answer 35

Dermatitis

Question 36

Polymyositis (PM): Sclerodactyly and ________ lung disease are common associated with this disease, but they are nonspecific to this disorder

Answer 36

Interstitial

Question 37

Polymyositis (PM): Affects primarily _______ muscles including shoulder and pelvic girdles, neck, pharynx _______ distribution

Answer 37

Proximal | Symmetrical

Question 38

Polymyositis (PM): Etiology is ________ - _________ reaction affecting muscle tissue with degeneration and regeneration, fiber atrophy, inflamm infiltrates

Answer 38

Unknown | Autoimmune

Question 39

Polymyositis (PM): | ______, severe onset: may requires vent assistance, tube feeding

Answer 39

Rapid

Question 40

Polymyositis (PM): | _______ involvement may be fatal

Answer 40

Cardiac

Question 41

Polymyositis (PM): Management: What meds?

Answer 41

Corticosteroids and immunosuppressants

Question 42

Polymyositis (PM): RED FLAG: Additional muscle fiber damage may result with too much _______ Contractures and pressure ulcers may results from prolonged ___ _____

Answer 42

Exercise | Bed rest

Question 43

Polymyositis (PM): PT ____ management and _____ conservation Aerobic/resistance exercise at ____ levels- avoid fatigue and overload ________ to prevent contractures and pressure ulcers

Answer 43

Fatigue, energy Low Positioning