Immune and Lymphoid Flashcards

1
Q

Immunocompetent cell

A

Cell that is able to recognize antigens and act against them

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2
Q

Immune response

A

How the body recognizes and defends against foreign substances and pathogens

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3
Q

Humoral immunity

A

Acquired immunity in which antibodies are secreted in response to antigenic stimulation.

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4
Q

cellular immunity

A

Immunological defense provided by T cells that come into close contact with their victim cells

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5
Q

Plasma cells

A

Cells derived from B lymphocytes that produce and secrete large amounts of antibodies. Responsible for humoral immunity

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6
Q

Memory cells

A

Cells derived from B or T cells that can quickly recognize a foreign antigen to which the body has been previously exposed.

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7
Q

Antigen-presenting cell (APC)

A

Immunocompetent cell that mediates the cellular immune response by processing and presenting antigens to T cells.

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8
Q

Waldeyer’s Ring

A

Pharyngeal, palatine and lingual tonsils which form a circle at entrance of gut and airway. Strategic, primary defense of lymphoid tissue

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9
Q

Peyers patches

A

Group of lymphoid nodules in the mucosa of the ileum that respond to foreign antigens.

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10
Q

Immunoglobulin/Antibody

A

Protein produced by B cells in response to unique antigen.

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11
Q

Antigen

A

Any substance that causes the immune system to produce antibodies against it.

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12
Q

Innate (natural) immunity

A

Most primitive an fast. Little specificity (programmed in germ line DNA). Results in direct killing of pathogens via macrophages, neutrophils, eosinophils and NK. Dysfunctional activation can lead to autoimmune dieases.

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13
Q

Adaptive immunity

A

Antigen specific immune response.

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14
Q

Immunodeficiency

A

Decreased or compromised ability to respond to antigenic stimuli with an appropriate immune response.

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15
Q

Follicular Cortex of lymph node

A
  • Rich capillary network

- B-cell zone

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16
Q

Parafollicular cortex of lymph node

A
  • Deep cortex
  • Rich capillary network
  • T-cell zone
17
Q

Medulla of lymph node

A
  • Rich with cells (macrophages, dendritic, pasta and B).
  • Highly branched network of thin reticular fibers provide physical support and network for mov’t of lymphocytes and dendritic cells
18
Q

Cortical sinuses

A
  • Receive fluid from afferent vessels.
  • Composed of trabecular, cortical and intermediate sinuses.
  • Contains macrophages and dendritic cells to perform phagocytosis.
19
Q

Medullary sinuses

A
  • Collect lymph after filtration in cortez

- Contains macrophages and antibodies

20
Q

Medullary cords

A

Contains the plasma cells that secrete antibodies into sinuses

21
Q

Red pulp

A

More abundant, main filtration functions.

22
Q

White pulp

A

Lymphatic nodules and diffuse lymph tissue. Synthesizes antibodies.

23
Q

Splenic Cords

A

Found in red pulp between sinusoids. Hold monocytes.

24
Q

Splenic Sinusoids

A

Endothelial cells arranged loosely in tubular form. Blood moves easily in and out as discontinuous.

25
Q

Thymus

A
  • Production of T lymphocytes

- Hormone secretion

26
Q

Thymus outer cortex

A

Full of developing thymocytes and macrophages

27
Q

Thymus medulla

A

Full of T cells

28
Q

Hassal’s corpuscles

A

Concentric, flattened epithelial reticular cells