Immune Flashcards

1
Q

IBS, Depression, recent ankle fractures - what are you suspicious of

A

celiac disease *associated with osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ankylosing spondylitis (AS) may be caused by an inappropriate immune response to what pathogen?

A

klebsiella pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what photochemcials and botanicals act as NF-kappaB (NFkB) inhibitor

A

Vitamin C, B12, and ALA, turmeric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the mechanism of quercetin?

A

stablizes mast cell membranes and reduces degranulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The activity of delta-6-desaturase (D6D), an enzyme that converts linoleum acid (LA) to GLA is impaired by what?

A

alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The four primary triggers for autoimmune disease are?

A

Trauma, infection, toxins, and foods. (genes are an antecedent)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How does glycemic lost increase inflammation?

A

via NF kB activation it can increase hsCRP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which botanicals function as NF-kappaB inhibitor?

A

Tumeric (curcuma longa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which fatty acid inhibits delta‐5‐desaturase?

A

Eicosapentaenoic acid (EPA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

A 43‐year‐old female with early rheumatoid arthritis is interested in adding one supplement to her diet that would help with her symptoms. She has already started a modified elimination food plan. Which is her best choice?

A

Omega 6
Borage, EPO (GLA)

Omega 3
flax, walnut, chia, hemp, soy (omega 3)
fish (EPA), fish/algae (DHA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

botanicals/phytonutrients with COX modulatory Properties

A

Bromelain, cayenne, ginger, rosemary, green tea, skullcap, teas-resveratrol, turmeric, feverfew, willow bark

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A 38‐year‐old female comes in with a diagnosis of lupus. You run a high‐sensitivity C‐reactive protein (hs‐CRP) and find that it is elevated. You place the patient on an elimination diet and also select two botanicals to decrease inflammation through their activity on cyclooxygenase (COX) enzymes. You choose

A

Bromelain and Ginger

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A 15‐year‐old male presents to your clinic with a history of asthma and an identified environmental trigger of grass pollen. Which foods could also exacerbate his asthma because of pollen‐food antigen crossover reaction?

A

Potatoes, tomatoes, and peaches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

A 26‐year‐old male presents to your clinic with concerns about gluten sensitivity. His mother and uncle both have biopsy‐proven celiac disease. He has been off gluten for three months. He brings in lab results that show negative serum anti‐endomysial and deaminated anti‐gliadin antibody tests. In order to rule out celiac disease in this individual, you recommend

A

HLA DQ2 and DQ8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

You are treating a 35‐year‐old female for psoriatic arthritis. You have made dietary changes and started her on EPA/DHA and vitamin D. You want to add two botanicals that act as anti‐inflammatories. The best choices are:

A

boswellia and bromelian

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Molecular mimicry results in

A

Development of autoimmunity

17
Q

An elimination diet, completed for a minimum of four weeks, addresses:

A

The clearance of IgE and IgG from the serum

18
Q

A 27-year-old male presents with chronic inflammation. You want to modulate the inflammatory cascade. Which combination of interventions would be useful to block phospholipase A2?

A

Vitamin E and quercetin

19
Q

A 37-year-old female patient presents with a chief complaint of an expanding list of food sensitivities that seem to be triggering eczema outbreaks. Which of the following is the most likely underlying cause of her eczema outbreaks?

A

Insufficient HCL production

20
Q

Select the statement that best describes the relationship of eicosapentaenoic (EPA) and docosahexaenoic (DHA) with systemic inflammation

A

EPA and DHA both reduce inflammation.

21
Q

Which of the following is most likely to stimulate NF-kappa-B production?

A

lipopolysaccarides

22
Q

Which of the following is a downstream metabolite of alpha-linolenic acid?

A

Eicosapentaenoic acid

23
Q

Which of the following are most likely to inhibit delta-6-desaturase enzymes?

A

Alcohol

24
Q

An elimination diet should be instituted for three to four weeks

A

Because the half-life of IgG antibodies in the serum is about 23 days.

25
Q

Is celiac disease associated with fracture risk?

A

yes via osteoporosis/malabsoption