ımmune Flashcards
what are the two branches of immune system
innate
adaptive
consisting of a series of organ;tissue and cells ;responcible for generate a immune response
immune system
innate immune system what it consists of
physical barriers
plasma proteins
phygocytic cells
chemical barriers secrations
chemical barriers of innate immune system ?
sweat
tallow
tears
saliva
physical barriers ?
skin
mucosal
phagocytic cells innate?
macrophages
neutrophils
natural killer cells
t cells progenitor?
memory t cell
cytotoxic T cell
helper T cell
hematopoietic stem cell?
lymphoid progenitor
myyloid progenitor
b cells progenitor ?
b memory
plasma cell
myeloid progenitor cell?
neutrophil
mast cell
basophil
eosinophil
moncyte
monocyte cells?
dendritic cell
macrophage
lineages of hemaopoietic stem cell?
myeloid
lymphoid
which system is slow response and its cells ?
adaptive immunity
T cell
B cell
natural killar t cell
which system is rapid rsponse and its cells?
mast cell
t cell
natural killer t cell
complement protein
macrophage
dendritic cell
basophil
eosinophil
neutrophil
epithelial
the first line of defence against anything recoized as non-self
innate immunity
protective mechanisms of innate immunity?
physical and chemical mechanisms
phagocytosis
molecular response
inflammatory response
physical barriers
intact skin
mucous membrane barrier
cilia
chemical barriers?
acid ph
bile
saliva
tears
phygocytosis
macrophages which engulf and kill invading organisms
dendritic cells which engukf pathogen
display antigen on cell surface
travel to lymph nodes to present antigen to t cell
critical link between the innate and immune responses
molecular response ?3
cytokines
chemokines
complement
small proteins made by a cell that effect the behavior og other cell?
cytokines
what csuae vsodilation heat and redness
cytokines
what causes redness ;swelling ;heat;and pain
inflammation
what increases the flow of lymphy and why?then it leads to adaptive immunity
inflammatory response
to take away microbes and antigen
accmulation of fluid and cells at the site of infection causes what
inflammation
redness
swelling
heat
pain
which cells secret histamine when it activated?
mast and basophils
mast and bisophils can be important //////to initial tissue damage as result of infection
inflammtory mediator
basophils is founded in
in the blood
mast cells are tissue resident in ?
mucosal tissues
called allergic response
mast and basophil
the cellular elements are represented by
phagocytes
plays a particular role in targeting larger infective organisms, such as parasitic worms.
eosinophil
detect and target intracellular infection of body cells by viruses
the natural killer cells
Recognition of microorganisms by the innate system occurs via
pamps on macrobil surface
prrs
tlrs
the classic pathway ;alternative; mannose-binding lectin pathway
complement system which represent the humoral arm of innate immunity
where is the complement system found
in solution in the blood
they can serve to both stimulate or inhibit the differentiation, proliferation or activity of immune cells
cytokines
play an important role in guding immune cells to sites of infection by forminf chemical trail
chemokines
seconed line of defence non-self
same pathogen
adaptive immunity
characteristics of adaptive immunity
specificity
tolerance
memory
anamnestic response
with subsequent exposure to an antigen there is rapid strong immune response
adaptive immune response consists of two branches
cellular adaptive response
humeroal adaptive response
cellular adaptive response effected by ?
effected by cytotoxic T cell
humoral adative response effected by?
b cell