Immediate Hypersensitivity Skin Testing Flashcards

1
Q

Immediate Hypersensitivity Skin Testing is what Type on the Gel and Combs scale?

A

Type I

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2
Q

How long does it take for a reaction to occur with Immediate skin testing?

A

15 Minutes

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3
Q

What are the precautions for Immediate Skin Testing?

A
  • Beta Blockers

- Certain Chronic Medical Conditions

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4
Q

What are the contraindications for Immediate Skin Testing?

A
  • Severe asthma attack in the past two weeks
  • Antihistimes
  • Pregnancy
  • Longtime Steroid Use
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5
Q

What are the two types of Immediate Skin Testing?

A
  • Prick

- Intradermal

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6
Q

What are the advantages of Prick Skin Testing?

A
  • Safer than ID
  • Minimal systemic absorption
  • Faster
  • Less tedious for the technician
  • Less discomfort for the patient
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7
Q

What are the disadvantages of prick skin testing?

A
  • Chance of Cross Contamination

- Chance of Cross Reaction

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8
Q

What is the strength of the positive control for prick skin testing?

A

2.75 mg/ml

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9
Q

What is used for the negative control for prick skin testing?

A
  • HSA

- Glycerin

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10
Q

What are the strengths of the extracts used for prick skin testing?

A
  • 10,000 - 20,000 PNU/mL

- 1:10 or 1:20 W/V

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11
Q

What are the locations used for prick skin testing?

A
  • Forearm

- Back

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12
Q

What are the two types of devices used for prick skin testing?

A
  • Quintip

- Dermaprick

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13
Q

When placing prick skin testing how far apart must each prick be placed?

A

1 inch

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14
Q

Once a Prick skin test has been placed how long must one wait to read the test?

A

15 Minutes

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15
Q

When reading the prick skin test it should always be measured ____________ X __________

A

Wheal X Flare

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16
Q

A prick test with a diameter greater than _______ is considered positive?

A

> 3 mm

17
Q

What would cause a false positive for immediate Hypersensitivity Skin Testing?

A
  • Technician Error
    • Excessive strength of antigen
    • Excessive dose of antigen
    • Cross contamination
  • Dermographic Patient
18
Q

What would cause a false negative for immediate Hypersensitivity Skin Testing?

A
  • Improperly prepared/stored extract
    • bottle/label contents mismatched
    • out dated extracts
  • Patient took antihistamines
  • Technician error
    • Improper placement
  • Intrinsic patient factors
    • leathery skin
19
Q

What are the advantages of Intradermal skin testing?

A
  • More Sensitive

- Less chance of cross contamination

20
Q

What are the disadvantages of Intradermal skin testing?

A
  • More dangerous
  • Causes more discomfort to the patient
  • More tedious for the technician
  • More irritant/ non-specific reactions
21
Q

What are the extract strengths used for ID testing?

A
  • 100 - 1,000 PNU/ml

- 1:500 or 1:1000 W/V

22
Q

What is the strength of the positive control for ID testing?

A

0.275mg/ml

23
Q

What is the positive control used for ID and prick skin testing?

A

Histamine

24
Q

What is the negative control used for intradermal testing?

A
  • Saline with HSA

- Saline with Phenol

25
Q

What location is used for intradermal testing?

A
  • Upper Arm- from the bend of the elbow to the middle of the deltoid
  • Forearm
  • Back
26
Q

What devices are used for intradermal testing?

A

Tuberculin Syringes

27
Q

When doing ID skin testing what amount of extract is drawn up?

A

0.05 mL

28
Q

When doing ID skin testing what amount is injected?

A

0.02 mL or the size of a 2mm bleb

29
Q

When can an ID test be read?

A

15 minutes after placement

30
Q

Venom ID testing can only be preformed under the direct supervision of a _____________?

A

Board Certified Allergist

31
Q

What venoms are available for testing?

A
  • Yellow Jacket
  • Yellow Hornet
  • White Faced Hornet
  • Wasp
  • Honey Bee
32
Q

Venom testing begins at what strength?

A

0.0001 mcg/ml

33
Q

What is the strongest strength used for venom testing?

A

1 mcg/ml