Imm: Exam IV quizzes Flashcards
Quiz 7
Recombination Activated Genes (RAG1/2) products RAG1/2 are critical for lymphocyte development. A person who carries mutant forms of them will
a) not be able to develop T cells
b) not be able to develop B cells
c) have severe immune deficient problems called Omen’s syndrome
d) have all a. b. and c.
e) have none of the above.
d) have all a. b. and c.
Quiz 7
The antigens that provoke hypersensitivity reactions are referred to as
a) T-independent antigens
b) allergens
c) superantigens
d) T-dependent antigens
e) haptens
b) allergens
slide 2
Quiz 7
All the statements below are correct EXCEPT___.
a) Some of the immunodeficiencies are dominant
b) Some of the immunodeficiencies are recessive
c) immunodeficiencies are X-linked
d) There are more than 150 immune gene mutations
e) All SCIDs (severe combined immune deficiency) are caused by RAG1/2 genes’ mutation.
e) All SCIDs (severe combined immune deficiency) are caused by RAG1/2 genes’ mutation.
Quiz 7
When a sensitized mast cell is activated, it will produce inflammatory mediators in two waves, immediate mediators and late phase mediators. These mediators include all of the following, EXCEPT____.
a) TNFa
b) Histamine
c) Prostaglandin
d) Interferon-γ
e) Leukotriene
d) Interferon-γ
slide 10
Quiz 7
Systemic anaphylaxis is caused by the presence of large amount of allergen in ___.
a) the gastrointestinal tract
b) the respiratory tract
c) the circulation
d) the skin
e) mismatched blood transfusions
c) the circulation
slides 16 & 17
Quiz 8
The mode of evolution responsible for the production of recombinant influenza viruses composed of a genome derived from two different influenza variants is called ___.
a) gene conversion
b) antigenic shift
c) latency
d) immune evasion
e) antigenic drift
b) antigenic shift
Quiz 8
An example of type III hypersensitivity is _____.
a) contact dermatitis
b) serum sickness
c) asthma
d) allergic rhinitis
e) tuberculin reaction
b) serum sickness
Quiz 8
The primary function of the autoimmune regulator (AIRE) is to _____.
a) facilitate apoptosis of self-reactive B lymphocytes in the bone marrow
b) activate the expression of tissue-specific proteins in the thymus
c) activate regulatory T cells
d) induce a state of no responsiveness in self-reactive T lymphocytes
e) participate in gene expression events required for positive selection of the developing T-cell repertoire.
b) activate the expression of tissue-specific proteins in the thymus
Quiz 8
_____ is the term used to describe how pathogen antigens resemble host antigens and can sometimes trigger autoimmune disease.
a) intramolecular epitope spreading
b) molecular mimicry
c) intermolecular epitope spreading
d) rheumatoid factor
e) auto-antibody
b) molecular mimicry
Quiz 8
The _____ occurs 6–8 hours after an initial type I allergic response, in which mast cells produce leukotrienes, chemokines, and cytokines.
a) late-phase reaction
b) delayed-type hypersensitivity reaction
c) condition known as anaphylactic shock
d) skin rash known as chronic urticaria.
a) late-phase reaction
