Imaging and Radiology (Lec 2) Flashcards
MAIN FOCUS: understand principles of contrast agents and the risk/reward for each imaging model
Xrays:
Wavelength length
Wave lengths are shorter than visible light (10picometers to 10 nanometers)
Why is there darker regions (eg lungs) and lighter regions on Xray
Xrays are stopped by dense tissues such as bones, preventing them reaching and reacting with the Xray sensitive surface
Non dense regions such as lung stop few Xrays and appear darker on the surface
Hazards of radiation exposure
Carcinogens, tetratogenesis, abortion, burn
Examples of structures/tissues etc that give these colours on xray
White
Grey
Darker grey
Black
White: Calcium, mineral, metal (eg bone)
Grey: Water/tissues (heart, liver)
Darker grey: Fat (eg subcutaneous)
Black: Air (eg lung)
What is haemarthrosis
Blood and fat in a joint
One drawback of Xray
Soft tissues arent seen well on Xray
Where can contrast material for Xrays be injected?
- Radio-opaque compounds are used to increase visualisation of structures
- For x-ray studies:
- introduce into cavities (e.g gut)
- Inject into blood vessels to to outline blood distribution
- Gut studies
- Barium Sulphate
- (Also Iodinated compounds)
All excreted by kidneys
What is Angiography
Contrast medium used to show vessels using Xray
How many dimensions is xray
single and often to get multiple angles
Benefits and risks of plain xray
Benefits:
Can be very imformative
Cheap
Avaiable
Fast to aquire
Risks
Structures are superimpsoed
Poor soft tissue definitaion
Radiation dose
Typically need 2 views
CT scans produces what kind of wavelength
Narrow continious fan shaped stream of X rays as it rotates around the head
CT scan
- what plane is used
Enables?
comapred to X ray its better how?
use X rays in transverse plane
Enables cross sectional imaging
Better contrast resolution than X rays
When to use contrast, thin or thick slices and window images (CT)
Looking at vascular structures or for enhancement: tumor etc use contrast
Looking at chest and lungs for masses use thick slice
Looking at lung parenchyma use thin slice
Window images for MAX contrast
Benefits and risks of CT Scan
Benefit:
Cross sectional imaging
Moderately avaiable
Fast to acquire
Can reformat
Risks:
Poor soft tissue def
Radiation in high dose
Moderately expensive
Perks of MRI for soft tissue
Gives great detail of soft tissue
- cortical dark bone = low signal
Can alter the manipulating pulse to change soft tissue contrast
DTI (diffusion tensor imaging)
what is it
DTI tractography of white matter tracts, uses diffusion anisotrophy to trace axon bundles
In sheer trauma acons are torn and tracts are disrupted
Benefits and risks of MRI
No ionising radiation
Excellent tissue contrast and spatial resolution
Ability to image any plane
Provide 3D images
Low avaibaility
Longer imaging time
high cost
Contraindications (pacemakers etc)
Nuclear medicine
What is it
Radioactive substances are injected or ingested into patient and gamma rays are detected with gamma camera
Examples of use of Nuclear medicine
Bone scans -fractures
V/Q scan for pulmonary embolism
Thyroid scan
White cell scans for infection
liver scans
renal scan
Brain scan - seizures
Technetium 99 bone scan
Part of NM where it absorbs onto crystalline hydroxyapatite of bone and degree of uptake depends on blood flow and rate of new bone formation
- shows metases, inflam, infection
PET scan (positron emission tomography)
Radioactive tracers (radioisotopes) accumulate in areas of higher metabolic activity
Ultrasound perks and risks
No ionising radiation
portable
ability to image in any plane
Easy to use
inepensive
widely avalibale
Longer imaging time
low resolution
operator dependent
Obstructed by air and bone
Use for ultrasound
Ab pain
Ab liver function tests
Swelling
palpable mass
renal dysfunction
screening for cancer
vascualr imaging
Causes of inappropriate x-ray exposure
- Studies that are unlikely to change patient management
- Repeated investigations
- Wrong investigations for condition
- Failure to provide appropriate clinical information
fresh blood is what colour on CT
White
how do you know if the scan is MRI or CT
CT = always have white bone
MRI = bone is black