Imaging and Pathological Correlates of Clinical Disease

Question 1

Describe a T1-weighted MRI:

Answer 1

Fat White
Fluid Black
Brain: grey intermediate, white hyperintense

Contrast: Gallinium
-Take up contrast white
Lesion outside BBB - even color all the way through

Question 2

Describe a T2- weighted MRI

Answer 2

Fluid = white
Fat= white

Help find pathology- change make tissue hyperintense
Inverse T1

Question 3

Why is MRI best for neurologic disease?

Answer 3

-Good at imaging soft tissue
-best contrast and resolution or neural structures
-Give morphological and function data about the nervous system
-Shows different features of lesions

Question 4

How does an MRI work?

Answer 4

The magnetic field is used to change the direction of the protons, then an RF signal changes the direction and a detector picks up the change

Question 5

High intensity =
Intermediate Intensity =
Low intensity =

Answer 5

White
Grey
Black

Question 6

What is isointense?

Answer 6

Same color as structures around it

Question 7

What are the types of planes of MRI?

Answer 7

Dorsal planar, transverse and sagittal

Question 8

T2-Weighted FLAIR

Answer 8

Fluid attenuated inversion recovery

Allows you to differentiate good fluid and back fluid

Pure fluid black
Path fluid white
fat white

Question 9

Susceptibility weigthed or sensitive - ferromagnetic blood is black - see hemorrhage

Answer 9

true

Question 10

PD or Proton density

Answer 10

actual density of proton in tissue
Low magnetic field - mix T1 and T2
Pure fluid - white
fat - white
flair