Image Registration Flashcards

1
Q

What is contrast resolution?

A

The ability to image differences among low contrast tissues

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2
Q

What is geometrical accuracy?

A

The ability to produce an image that is a geometrically correct
representation of the object imaged

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3
Q

What is spatial resolution?

A

The ability to identify an object as distinct and separate from
another object

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4
Q

What is Sensitivity?

A

The ability to detect differences in an object

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5
Q

Specificity

A

The ability to accurately determine the nature of the imaged object

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6
Q

What is a T1 weighted image?

A

spin-lattice or longitudinal relaxation
time.

Depicts anatomy well (low sensitivity for disease without contrast)

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7
Q

What is a T1 weighted image?

A

spin-spin or transverse relaxation
time.
Depicts diseases with high water content well (low specificity though)

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8
Q

What is a proton density weighted image?

A

Depicts anatomy and disease well (currently limited applications).
Higher spatial resolution than T1 and T2.

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9
Q

What is a spin echo (SE) and fast/turbo SE.

A

INCREASES spatial resolution and reduce artifacts caused by magnetic field and inhomogeneties.

Fast SE is preferred for RT - it is faster and reduces motion artifacts

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10
Q

What is a gradient echo?

A

Very short acquisition time minimises motion artifacts, DECREASE spatial
resolution; used for multi-phased imaging, oxygenation levels

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11
Q

What is diffusion weighted imaging (DWI)

A

Differentiating between ↑cellular density (tumours) and ↓cellular
density (benign tissues inflammation necrosis

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12
Q

What is the difference between a T1 and T2 image?

A

T1 fat is white

T2 fluid is white

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13
Q

What colour is fat in a T2 fast spin echo (FSE) image

A

Fat is bright

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14
Q

What are MRI limitations?

A

Image distortion due to non-uniformities
in the magnetic field

Image quality dependence on coils. ( this is a problem for RT imaging requirements e.g. fitting immobilisation under coils.

Poor imaging of cortical bone.

MRI distortion

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15
Q

What common radionucleiode is used for PET scanning?

A

FDG (fluoro-D-glucose).

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16
Q

What are the limitations of PET?

A

High uptake in benign pathologies.
Image resolution musch poorer than CT ( difficult to delineate tumour volumes).
PET is a metabolic image

17
Q

Why does PET have a poor image resolution?

A

PET uses a relatively large voxel size (0.4x0.4x0.4)
Images appear pixelated compared to CT.
(Difficult to define a geometric edge)

18
Q

What is semi-automated rigid image registration?

A

Use of automatic translational functions

to match landmarks and/or surfaces

19
Q

What is automates rigid image registration?

A

Use of algorithms to perform matching
based on statistical analysis or signal
processing of the voxel data of the two
image sets

20
Q

What are the 2 most common algorithms used in automated image registration?

A

Cross Correlation

Mutual Information

21
Q

What is cross correlation?

A

Used for registering an image with similar information.
Best suited to registering intra-modality images (CT-CT or MRI-MRI) registration.
Can be used CT-MRI

22
Q

What is mutual information?

A

Used for registering images with dissimilar information.
Technically this algorithm can be used for all multi-modality image registration.
Most commonly used for CT-PET or MRI-PET registration.