II. Fisiopato diabetes Flashcards

1
Q

Dx de diabetes (3)

A
  • Clínica + >200 mg/dL cualquier hora
  • > 126 mg/dL ayunas (se repite)
  • > 200 mg/dL post carga
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2
Q

DM1 está influenciada por

A
  • Genética
  • Ambiente
  • Sist. Inmune
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3
Q

Fisiopato DM1

A

Agente estimulador (infección, AI) -> Células T -> Destrucción Beta cells -> Hiperglicemia

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4
Q

Una alteración del microbioma puede llevar a ….

A

DM2

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5
Q

Factor de riesgo de DM2 en el RN

A

Bajo y sobrepeso

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6
Q

Tejido sensible a insulina

A
  • Hepático
  • Muscular esquelético
  • Adiposo
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7
Q

Moléculas celulares afectadas en RI

A
  • IRS

- AKT

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8
Q

Causa de la pérdida de Beta cells

A
  • Acumulación de polipéptido amiloide (amilina)
  • Acumulación de A. grasos
  • Hiperglicemia
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