IgM Flashcards
Revision
1
Q
Structure?
A
pentameric
10 Ag binding site
60 CDR
2
Q
Stability because of?
A
S-S bond
and J-chain
3
Q
J chain in IgM
A
1 J chain
137 aa
15 KDa
4
Q
J chain responsible for?
A
polymerisation
5
Q
No. of Ag binds to IgM?
(If size is not mentioned)
A
5
6
Q
No. of small Ag binds to IgM?
A
10
7
Q
Concentration?
A
5-10% of total serum
8
Q
oldest Ig?
A
IgM
9
Q
Neopnate produce which Ig first?
A
IgM
10
Q
formed during?
A
during primary response
11
Q
Most effective complement activator
A
IgM
expose 3 Binding site @ CH2 domain
12
Q
A