Antigen Determinant Flashcards

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1
Q

Ag Determinants

A

Antigenic determinants, also known as epitopes, are specific regions on the surface of an antigen that are recognized and bound by antibodies or T-cell receptors.

Each antigen can have multiple epitopes, allowing the immune system to target it in different ways.

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2
Q

3 Ag Determinant

A

Isotype
Idiotype
Allotype

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3
Q

Isotype

A

Isotypes determine the functional properties of the antibody and its role in the immune response.

The five main isotypes in humans are:

IgG
IgA
IgM
IgE
IgD
Each isotype has a unique role in the immune system, such as neutralizing pathogens, activating complement, or mediating allergic reactions.

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4
Q

Idiotype`

A

These unique determinants (epitopes) define the antibody’s ability to recognize and bind to a specific antigen. The idiotype is different for each antibody, even if the antibodies belong to the same isotype.

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