IgA Nephropathy Flashcards
To learn about this
1
Q
What is IgA nephropathy?
A
- Also called Bergers disease or mesangioproliferative glomerulonephrits
- Commonest cause worldwide
- Caused by mesangial deposition of IgA complexes
- Overlap with Henoch-Schonlein purpura
- Mesangial hypercellularity
2
Q
How does IgA present?
A
- Young male
- Associated with mucosal infections
- Renal failure
3
Q
Differential diagnosis between IgA nephropathy and post strep glomulonephritis?
A
- PSG assoc with low complement levels: main symptom is proteinuria
- PSG develops 2 weeks or so after URTI rather than 1/2 days
4
Q
What gives red blood cell casts?
A
Glomerulonephritis, Renal ischemia and infarction
5
Q
What gives white blood cell casts?
A
Acute pyelonephritis, interstitial nephritis
6
Q
What gives granular (muddy brown) casts
A
Acute tubular necrosis
7
Q
What gives hyaline casts?
A
Common and non specific, maybe seen on exercise/dehydration
8
Q
What causes epithelial casts
A
Acute tubular necrosis
9
Q
What causes waxy casts?
A
Advanced chronic kidney disease
10
Q
What causes fatty casts?
A
Nephrotic syndrome
