Idk Yet Flashcards
DNA replication
The copying of double stranded DNA and necessary for cell reproduction prior to cell division 
What is semi conservative?
The resulting DNA copies, each have one strand of parental DNA, and one newly constructed strand
Helicase
Separates DNA strands
SSB
Single strand binding proteins, or SSPs, are tetramers that coat the DNA this prevents the DNA strands from reannealing to form double stranded, DNA 
Primase
Creates RNA primers
Polymerase
Strings nucleotides together to form a DNA strand 
(Extends DNA chain)
Sliding clamp
proteins that helps hold the DNA polymerase onto the DNA strand during replication 
RNase H
removes the RNA primers that previously began the DNA strand synthesis 
Ligase
Links short stretches of DNA together to create one long, continuous DNA strand
Steps of DNA replication
- Strands are separated
- SSBs coat single strands
- Primaries synthesizes RNA primers. 
- Polymerase attaches nucleotide at three prime, end
Synthesis begins in the 5 to 3 direction - One strand synthesizes continuously, while the lagging strand synthesizes Discontinuously 
- RN, ace H removes RNA primers.
- DNA polymerase I fills the gaps where RNA primers were removed 
DNA pieces separated by RNA primers in lagging strand are called
Okazaki fragments

Why is primase necessary
Polymerase can only extend a nucleotide chain and not start one. Primates uses the original DNA as a template to create a short and RNA primer