Idiosyncrasy Flashcards
What is idiosyncrasy?
Idiosyncrasy refers to an abnormal reactivity to a chemical or drug that is genetically determined. It is a unique reaction specific to certain individuals and not commonly observed in the majority of the population.
How does idiosyncrasy occur?
Idiosyncrasy occurs when a drug interacts with a unique feature or characteristic of an individual, which is not present in most people. This interaction leads to an uncharacteristic or unusual reaction to the drug
Which individuals experience excitement and mental confusion when taking barbiturates?
Some individuals experience excitement and mental confusion when taking barbiturates, despite their typical sedative effects on most people
What are the adverse effects caused by quinine/quinidine in some patients?
In some patients, quinine/quinidine can cause cramps, diarrhea, purpura (purple spots on the skin), asthma, and vascular collapse
What serious condition can rare individuals develop as a result of taking chloramphenicol?
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In rare individuals, chloramphenicol can cause a serious condition called aplastic anemia, which is not related to the dosage of the drug