Idiopathic dilated cardiomyopathy Flashcards
1
Q
What is it?
A
wastebasket category
nonspecific end-stage heart disease
with cardiac dilatation and heart failure
no cause evident
2
Q
epidemiology
A
ages 20-60 at diagnosis
3
Q
presentation
A
slowly progressive heart failure OR
acute decompensation
4
Q
Gross pathology
A
heart:
- -enlarged
- -soft “flabby”
- -4 chamber dilatation
- -mural thrombi
5
Q
Microscopic pathology
A
myocyte degeneration
myocyte atrophy
other myocytes w/ irregular hypertrophy
interstitial and perivascular fibrosis
**findings can be surprisingly minimal
6
Q
Symptoms
A
nonspecific symptoms of HF
7
Q
Signs
A
tachycardia
leftward displaced diffuse PMI
S3
murmurs of mitral and tricuspid regurg
arrhythmias
Sudden death
8
Q
diagnosis
A
only after all specific causes of dilated cardiomyopathy are ruled out
“diagnosis of exclusion”
9
Q
Treatment
A
salt restriction diuretics vasodilators digoxin amiodarone implanted defibrillator anticoagulation transplantation
