ID Flashcards
Chancroid: cause?
Haemophilus ducreyi
Chancroid: Clinical presentation
Painful
Shallow, friable, nonindurated with ragged margins, granulomatous base, yellow or gray, necrotic purlent exudate
Chancroid: associated symptoms
Painful inguinal adenopathy called “buboes” present
Chancroid: diagnosis
Culture of lesion. not widely available)
CDC criteria for diagnosis:
1. >1 painful genital ulcer
2. No evidence of syphilis on dark-field or serologic test performed 7 days after onset of ulcer
3. Typical clinical presentation
4. Negative HSV test of ulcer
Lymphogranuloma venereum: Cause?
L1 L2 or L3 forms fo C. trchomatis
Lymphogranulmoa venerum: Clinical presentation?
Painless ulcer, small pustule at site of inoculation, can disappear rapidly
lymphogranuloma venereum: Associated symptoms
First stage: small, painless ulcer
Second stage: constitutional illness, painful lymphadenopathy, “groove” sign pathognomonic
Third stage: proctocolitis
Lymphogranuloma venereum: Diagnosis
Genital lesion swab lymph node aspirate tested using nucleic acid amplification tests
Granuloma inguinale: cause?
Klebsiella granulomatis
Granuloma inguinale: clinical presentation?
Painless, slowly progressive ulcerative lesion on genitals or perineum; bleeds easily on contact
Grauloma inguinale: associated symptoms
Regional lymphaenopahty is uncommon
Granuloma inguinale: diagnosis
Identification of Donovan bodies within histiocytes of granulation tissue smears or biopsy specimens
Syphilis: cause/
Treponema pallidum
Syphilis: clinical presentation
Painless ulcer with indurated hard, raised border and “punched-out” appearance
Syphilis associated symptoms
regional lymphadenopathy may occur
Syphilis: diagnosis
Screen: nontreponemal tests (RPR, VDRL)
Confirm: treponemal tests (FTA-ABS or TPPA)
Dark-field microscopy showing spirochetes
Genital herpes: cause?
HSV1 or HSV2
Genital herpes clinical presentation
Painful vesicular lesions developing into ulcer