ICD Flashcards
What were our secondary prevention trials?
AVID
CASH
CIDS
What were our primary prevention trials?
MADIT MADIT II MUSTT SCDHEFT COMPANION
What did AVID look at?
AAD vs ICD
What were the AAD included in AVID?
Amiodarone
Sotalol
In AVID, what was % reduction in mortality due to arrhythmias?
56%
In AVID, what was the % reduction in overall mortality?
31%
What did CASH look at?
AAD vs ICD
What were the AAD included in CASH?
Amiodarone
Propafenone
Metoprolol
Which drug was discontinued in CASH?
Propafenone
In CASH, what was the % reduction in mortality due to arrhythmias?
58%
In CASH, what was the % reduction in overall mortality?
23%
What did CIDS look at?
AAD vs ICD
What was the AAD in CIDS?
Amiodarone
In CIDS, what was the % reduction in mortality due to arrhythmias?
33%
In CIDS what was the % reduction in overall mortality?
20%
In CIDS, what was the % of the amio group that later had an ICD implanted?
20%
What is the inclusion criteria for MADIT?
Prior MI
<30%
What did MADIT look at?
ICD vs OPT (Amio)
In MADIT, what was the % reduction in mortality due to arrhythmias?
75%
In MADIT, what was the % reduction in overall mortality?
54%
What was the inclusion criteria for MADIT II?
> 21 y/o
Prior MI
<30%
What did MADIT II look at?
ICD vs OPT
In MADIT II, what was the % reduction in mortality due to arrhythmias?
62%
In MADIT II, what was % reduction in overall mortality
31%
