ICD Flashcards

1
Q

What were our secondary prevention trials?

A

AVID
CASH
CIDS

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2
Q

What were our primary prevention trials?

A
MADIT
MADIT II
MUSTT
SCDHEFT
COMPANION
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3
Q

What did AVID look at?

A

AAD vs ICD

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4
Q

What were the AAD included in AVID?

A

Amiodarone

Sotalol

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5
Q

In AVID, what was % reduction in mortality due to arrhythmias?

A

56%

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6
Q

In AVID, what was the % reduction in overall mortality?

A

31%

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7
Q

What did CASH look at?

A

AAD vs ICD

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8
Q

What were the AAD included in CASH?

A

Amiodarone
Propafenone
Metoprolol

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9
Q

Which drug was discontinued in CASH?

A

Propafenone

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10
Q

In CASH, what was the % reduction in mortality due to arrhythmias?

A

58%

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11
Q

In CASH, what was the % reduction in overall mortality?

A

23%

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12
Q

What did CIDS look at?

A

AAD vs ICD

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13
Q

What was the AAD in CIDS?

A

Amiodarone

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14
Q

In CIDS, what was the % reduction in mortality due to arrhythmias?

A

33%

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15
Q

In CIDS what was the % reduction in overall mortality?

A

20%

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16
Q

In CIDS, what was the % of the amio group that later had an ICD implanted?

A

20%

17
Q

What is the inclusion criteria for MADIT?

A

Prior MI

<30%

18
Q

What did MADIT look at?

A

ICD vs OPT (Amio)

19
Q

In MADIT, what was the % reduction in mortality due to arrhythmias?

A

75%

20
Q

In MADIT, what was the % reduction in overall mortality?

A

54%

21
Q

What was the inclusion criteria for MADIT II?

A

> 21 y/o
Prior MI
<30%

22
Q

What did MADIT II look at?

A

ICD vs OPT

23
Q

In MADIT II, what was the % reduction in mortality due to arrhythmias?

A

62%

24
Q

In MADIT II, what was % reduction in overall mortality

A

31%

25
Q

What did SCDHEFT look at?

A

ICD vs OPT vs Amiodarone

26
Q

What was the inclusion criteria for SCDHEFT?

A

Class II III

<35%

27
Q

In SCDHEFT, what was % reduction in mortality due to arrhythmias?

A

64%

28
Q

In SCDHEFT, what was the % reduction in overall mortality?

A

23%