IBD 81

Question 1

HLA Haplotypes associated with IBD

Answer 1

HLA B27

Question 2

Type of anemia present in Crohn’s disease

Answer 2

Normocytic normochromic

Question 3

Antibody present in serology of Crohn’s disease

Answer 3

Saccharomyces cerevisiae

Question 4

Antibody present in serology of Ulcerative Colitis

Answer 4

P-ANCA

Question 5

What is the cheap, non invasive marker of disease activity in IBD?

Answer 5

Fecal Calprotectin

Question 6

What is the effective drug in patients with corticosteroids/ immunosuppressives resistant Crohn’s disease? (used for remission not maintenence)

Answer 6

MTX.
Cyclosporine

Question 7

First line Tx in cases of moderate to severe activity in Crohn’s disease

Answer 7

Biological Tx : Infliximab

Question 8

All patients with ulcerative colitis should be treated with…..

Answer 8

Amino salicylate (5-asa)

Question 9

First line Treatment in case of Proctitis

Answer 9

Oral aminosalicylates + local steroid preparation

Question 10

Management of total colitis in ulcerative colitis

Answer 10

. Admission
. Hydrocortisone 100mg iv every 6 hrs
. Oral aminosalicylates.

Question 11

Management of patients with Ulcerative colitis in whom Toxic dilatation has not resolved within 48 hrs.

Answer 11

Urgent surgery

Question 12

How frequent should patients with extensive ulcerative colitis for >10 yrs undergo colonoscopy and multiple biopsies?

Answer 12

Every 1-2 yrs

Question 13

Test used for detection of H. Pylori in stomach

Answer 13

Rapid Urease test

Question 14

When should tests for confirmation of eradication of H. Pylori be done?

And what is the drug that must be stopped for 2 weeks before testing?

Answer 14

. After 4 weeks of treatment
. PPI