IBD

Question 1

What is used to induce remission in Crohns?

Answer 1

1. Glucocorticoid steriods
2. 5 asa
   Add on: azathioprine or mecaptopurine

Question 2

What is used to maintain remission in Crohns?

Answer 2

1. Azathioprine* or mecaptopurine*
2. Methotrexate

*assess TPMT level before starting

Question 3

What is used to induce remission in UC?

Answer 3

If just rectal: rectal mesalizine

1. Oral aminosalicylates
2. Wait 4 weeks then Oral prednisolone

Severe flare
1. IV steriods in hospital

Question 4

How to maintain remission in UC?

Answer 4

1. Oral aminosalicylates

2. Azathioprine and mercaptopurine

Question 5

Seen on enema in UC?

Answer 5

Pseudopolyps

Question 6

Seen on enema in Crohns?

Answer 6

Strictures kantor string sign, rose thorn ulcers, fistula

Question 7

Seen on histology in Crohns

Answer 7

Goblet cells

Granulomas

Question 8

Seen on histology in UC

Answer 8

Crypt abscess

Inflammatory cell infiltration in the lamina propria