IBD

Question 1

Crohns defining features (NEST’S)

Answer 1

N - No blood or mucus
E - Entire gastrointestinal tract affected
S - Skip lesions on endoscopy
T - Terminal ileum most affected and Transmural inflammation
S - Smoking is a risk factor

Also associated with strictures and fistulas

Question 2

Ulcerative colitis (CLOSE UP)

Answer 2

C - Continuous inflammation
L - Limited to the colon and rectum
O - only the superficial mucosa affected
S - Smoking may be protective
E - Excrete blood and mucus
U - Use aminosalicylates
P - Primary sclerosis cholangitis is associated

Question 3

IBS definition

Answer 3

involves recurrent episodes of inflammation in the gastrointestinal tract.

Both associated with period of exacerbation and remission

Question 4

IBS cause

Answer 4

Combination of factors related to genetics, environment and the gut microbiome

Question 5

general presenting features

Answer 5

Diarrhoea
Abdominal pain
Rectal bleeding
Fatigue
Weight loss

Question 6

Ulcerative colitis treatment (mild - moderate)

Answer 6

Aminosalicylate (mesalazine)
Corticosteroids (prednisolone)

Question 7

Ulcerative colitis treatment (severe)

Answer 7

Intravenous steroids (hydrocortisone)
Intravenous ciclosporin
infliximab
surgery

Question 8

Crohns Treatment

Answer 8

Steroids
Enteral nutrition (treating deficiencies, improving gut microbiome, removing inflammatory foods)

Question 9

How to test for IBD

Answer 9

Faecal calprotectin is around 90% sensitive and specific for IBD. it is used as the initial test before doing an endoscopy

Question 10

Ulcerative colitis treatment via surgery

Answer 10

surgery can be used for UC as it usually only affects the large bowel and rectum. this surgery is called a panproctolectomy.

The patient is fitted with an ileostomy or an oleo-anal anastomosis