IBD

Question 1

IBD is compromised of which two major disorders?

Answer 1

Ulcerative colitis and Crohn’s disease

Question 2

What part of the GI tract does Ulcerative Colitis effect?

Answer 2

Colon

Question 3

What part of the GI tract does Crohn’s Disease effect?

Answer 3

Any component of the GI tract (from mouth to perianal area)

Question 4

IBD is more common in which geographic regions?

Answer 4

Canada, Northern Europe, America
*higher in Northern latitudes than Southern

Question 5

Which populations have greater instances of IBD?

Answer 5

-Greater in Jewish (Ashkenazi descent) compared to non-jewish
-Caucasian > hispanic, AA, Asian

Question 6

Is UC more common in men or women?

Answer 6

Men

Question 7

Is Crohns (CD) more common in men or women?

Answer 7

Women

Question 8

Age of onset for IBD?

Answer 8

15-35 years (but can occur at any age)
-> possible second peak at >55 y/o

Question 9

Incidence of IBD is highest in _____ countries, and lowest in ______ regions?

Answer 9

Highest: developed countries
Lowest: developing regions

Question 10

DDX for IBD?

Answer 10

Colorectal cancer, IBS, Infectious/ischemic/radiation colitis, Microscopic colitis, Amebiasis, med side effects, Pseudomembranous colitis (C. diff), Toxic megacolon, Appendicitis, Celiac, Bacterial overgrowth

Question 11

What is ulcerative colitis (UC)?

Answer 11

Chronic inflammatory condition characterized by relapsing and remitting episodes of inflammation (ulcers) to the mucosal (mucosa/submucosa) layer of the large intestine (colon)
*almost always involves the rectum

Question 12

Pattern of UC?

Answer 12

Circumferential and continuous:
-usually starts distally at rectum & extends proximally in continuous pattern to involve other parts of the colon

Question 13

As UC becomes chronic, the colon loses haustral markings lading to what type of appearance?

Answer 13

Lead pipe appearance of colon (seen on Barium enema)