Ian Illingworth Flashcards
What does the hepatic vein do
Carries deoxygenated blood to inferior vena cava
What do the left and right hepatic ducts do
Drain bile into the common hepatic duct
What does the hepatic portal vein do
Carries blood from spleen and GI tract to liver
What does the hepatic artery do
Carries oxygenated blood to liver from heart
What is the duct from gall bladder to common hepatic duct
Cystic duct
What are the exocrine hormones secreted by the liver
What do they do
Somatomedin- growth factor
Angiotensinogen- pre cursor to angiotensin which increases blood pressure
Thrombopoetin- platelet production
Hepcidins- blocks iron release
What is the exocrine function of the live
Produces and secretes bile into small intestine via common hepatic duct
Outline the metabolic function of the liver in terms of carbohydrates
Glycogenesis stimulated by insulin
Glycogenolysis stimulated by glucagon
Outline lipolysis in the liver
Lipids absorbed within chylomicron in small intestine are exocytosed and travel through lactiles to thoracic duct to liver where lipids broken down into fatty acids by lipolysis
Which lipids are synthesised in the liver
3
Lipoproteins
Phospholipids
Cholesterol
What proteins are synthesised in the liver
5
Clotting factors Carrier proteins Immune system proteins Albumin Amino acids
Which vitamins does the liver store
5
Which minerals does the liver store
2
A, D, E, K, B12
Iron
Copper
How long are vitamins A and B12 stored in liver
Up to 4 years
How does the liver detoxify ammonia
3
Ammonia produced in intestines
Travels to liver by hepatic portal vein for ornthine cycle
Urea taken time kidneys through circulation
How does the liver detoxify ethanol
Alchohol dehydrogenase converts ethanol to acetaldehyde
How does the liver detoxify drugs
Cytochrome P450 enzymes
What are the phases of digestion and what occurs at each phase and when does each stage happen
Cephalic phase- when food is seen, smelled or thought about- vagus nerve stimulates pancreatic secretions in preperation for digestion
Gastric phase- when food eaten- digestion in stomach stimulates pancreatic secretions
Intestinal phase- when food digested- presence of H+, amino acids and fatty acids stimulates CCK and secretin which stimulate pancreatic secretions
Secretions inhibited- somatostatin and decreasing chyme macronutrients
What substances are secreted by acinar cells of pancrease and how do they ease digestion
3
Zymogen granules: contain digestive enzymes
Sodium ions: water levels in duodenum increase by osmosis
Bicarbonate: increases pH of chyme as enzymes in duodenum need higher pH
Where does bile from common hepatic duct drain into when sphincter of oddi relaxed
Duodenum
Where does bile from common hepatic duct drain into when sphincter of oddi contracted
Gall bladder via cystic duct
What does CCK stimulate in the hepatobillary system
2
Gall bladder contraction
Sphincter of oddi relaxation
What component of bile gives it its colour
Bilirubin
What do bile salts do
What do phospholipids do
Emulsifies fats
Soulubises bile salts
What does red pulp of spleen do
What does white pulp of spleen do
Stores blood in case of haemorrhage , filters blood and removes defective red blood cells
Contains lymphoid tissue that produces antibodies and removes antibody coated bacteria or cells
What structures are at level of C3
Hyoid bone
Bifurcation of common carotid artery
Where is the larynx
C4-C6
Where is thyroid cartilage
C4
Where is the isthmus of thyroid gland
C6
What nerve innervates anterior belly of digastric
Mandibular nerve
What nerve innervates posterior belly of digastric
Facial nerve
What nerve innervates sternomastoid
Accessory nerve
What nerve innervates trapezius
Accessory nerve
What nerve innervates omohyoid
C1-C3
What are the triangles of the anterior neck triangles
4
Submental
Submandibular
Carotid
Muscular
What is the borders of the anterior triangle
Lower border of mandible
Midline of neck
Sternomastoid
What are the borders of the submental triangle
4
Body of hyoid bone
Anterior belly digastric
Midline of neck
Lower border of mandible
What are the contents of submental triangle
5
Mylohyoid nerve Lymph glands Submental lymph nodes Submental branch of facial artery Submental branch of facial vein
What are the borders of the submandibular triangle
3
Lower border of mandible
Anterior belly digastric
Posterior belly digastric
What are the contents of the submandibular triangle
8
Submandibular gland Submandibular lymph nodes External carotid artery Internal carotid artery Facial artery Facial vein Hypoglossal nerve Facial nerve
What are the borders of the carotid triangle
3
Sternomastoid
Omohyoid
Posterior belly digastric
What are the contents of the carotid triangle
7
Common carotid artery Internal carotid artery External carotid artery Internal jugular vein External jugular vein Hypoglossal nerve Vagus nerve
What are the borders of the muscular triangle of the neck
3
Midline of neck
Omohyoid
Sternomastoid