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Anesthesia Pharm > IA Comparison > Flashcards

IA Comparison Flashcards

1
Q

VA most decrease CMRO2

A

all equallY

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2
Q

Compare VA with regard to their effects on blood flow

A

all equally

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3
Q

LEAST likely to produce potentially dangerous increases in ICP if modest hypocapnia is present

A

Isoflurane

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4
Q

most likely to produce coughing in an LMA intubation

A

Isoflurane

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5
Q

VA that is completely halogenated

A

Desflurane

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6
Q

which VA least potentiate muscle relaxants?

A

ALL OF modern VA

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7
Q

How are VA carried in the blood

A

dissolved

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8
Q

At 30 mins what is the FA FI for each inhalation agent at a constant inspired concentration?

A

Iso: 0.73, Sevo, 0.85, Des: 91

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9
Q

Brain uptake of anesthetic depends on what four factors?

A
  1. Blood Solubility –> the higher the solubility the slower the uptake
  2. Cardiac Output
  3. Alveolar ventilation –> increasing the ventilation speeds uptake
  4. Inspired concentration –> increasing inspired concentration speeds brain uptake
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10
Q

List 7 factors that decrease MAC

A
  1. Increasing Age
  2. Hypothermia
  3. CNS depressants
  4. Acute ethanol intoxication
  5. Alpha-2 agonists
  6. Pregnancy
  7. decrease levels of CNS excitatory neurotransmitters
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11
Q

List three factors that increase MAC

A
  1. Hyperthermia
  2. Hypernatremia
  3. Increased levels of CNS excitatory neurotransmitter as would occur with cocaine use or the administration of MAOI
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12
Q

What are the MAC requirements for a full-term infant, compared to the adult?

A

The MAC value for a full-term infant is the same as for the adult

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13
Q

Three renal changes associated with administration of VA

A

decrease in

  1. renal blood flow
  2. glomelular filtration rate
  3. urine outout
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14
Q

How are VA metabolized?

A

by the CYP 450 also known as mixed- function oxidases

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15
Q

arrange from greatest to least with respect to the production of carboxyhemoglobin

A

desflurane > isoflurane

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16
Q

Which two modern volatile anesthetics have only flourine as the halogen substitution?

A

Des and Sevo

17
Q

Which two volatile anesthetics most decrease SVR

A

Isoflurane and Des

18
Q
A

Anesthesia Pharm (25 decks)

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