IA Comparison Flashcards
VA most decrease CMRO2
all equallY
Compare VA with regard to their effects on blood flow
all equally
LEAST likely to produce potentially dangerous increases in ICP if modest hypocapnia is present
Isoflurane
most likely to produce coughing in an LMA intubation
Isoflurane
VA that is completely halogenated
Desflurane
which VA least potentiate muscle relaxants?
ALL OF modern VA
How are VA carried in the blood
dissolved
At 30 mins what is the FA FI for each inhalation agent at a constant inspired concentration?
Iso: 0.73, Sevo, 0.85, Des: 91
Brain uptake of anesthetic depends on what four factors?
- Blood Solubility –> the higher the solubility the slower the uptake
- Cardiac Output
- Alveolar ventilation –> increasing the ventilation speeds uptake
- Inspired concentration –> increasing inspired concentration speeds brain uptake
List 7 factors that decrease MAC
- Increasing Age
- Hypothermia
- CNS depressants
- Acute ethanol intoxication
- Alpha-2 agonists
- Pregnancy
- decrease levels of CNS excitatory neurotransmitters
List three factors that increase MAC
- Hyperthermia
- Hypernatremia
- Increased levels of CNS excitatory neurotransmitter as would occur with cocaine use or the administration of MAOI
What are the MAC requirements for a full-term infant, compared to the adult?
The MAC value for a full-term infant is the same as for the adult
Three renal changes associated with administration of VA
decrease in
- renal blood flow
- glomelular filtration rate
- urine outout
How are VA metabolized?
by the CYP 450 also known as mixed- function oxidases
arrange from greatest to least with respect to the production of carboxyhemoglobin
desflurane > isoflurane
Which two modern volatile anesthetics have only flourine as the halogen substitution?
Des and Sevo
Which two volatile anesthetics most decrease SVR
Isoflurane and Des
