anti Fungal Flashcards
What is Candida?
Candida is a yeast
What are samples of Mold
Mucor
Aspergillus
What is Amphotericin B?
Amphotericin is a POLYENES
What does Amphotericin B cover?
DOC
WHATS THE SALVAGE THERAPY COVERAGE?
adverese SE??
MUCOR (DOC)
- treat with surgical resection -
ASPERGILLUS (SECOND LINE)
CANDIDIASIS (SECOND LINE)
adverese se: renal failure! hypo K hy po MAG
hydrate before and after each dose with NS
Fluconazole
DOC for:
Candidiasis albicans!!(DOC)
GLOBRATA VERY COMMON CANDIDA TO SEE IN OR
–> massive doses of fluconazole to overcome resistance of Globrata (finicky)
does not cover: aspergillus, kruseie, mucor
Adverse effect of Fluconazole
Hepatotoxicity
Qtc prolongation
What is the DOC for Aspergillus?
adverese SE:?
Voriconazole
SE: DELIRIUM, HALLUCINATION
ISAVUCONAZOLE can be used for?
Aspergillus and Mucor
claim to fame: “azole” with shortened Qtc
Big things for Echinocandins
first-line agent for CANDIDA GLOBRATA
What are the samples of Echinocandins?
“Fungin”
Caspofungin
Micafungin – poor penetration of urine
Andulafungin
- first line for Candida Globrata -