anti Fungal Flashcards

1
Q

What is Candida?

A

Candida is a yeast

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2
Q

What are samples of Mold

A

Mucor

Aspergillus

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3
Q

What is Amphotericin B?

A

Amphotericin is a POLYENES

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4
Q

What does Amphotericin B cover?

DOC

WHATS THE SALVAGE THERAPY COVERAGE?

adverese SE??

A

MUCOR (DOC)

  • treat with surgical resection -

ASPERGILLUS (SECOND LINE)

CANDIDIASIS (SECOND LINE)

adverese se: renal failure! hypo K hy po MAG

hydrate before and after each dose with NS

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5
Q
A
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6
Q

Fluconazole

DOC for:

A

Candidiasis ​albicans!!(DOC)

GLOBRATA VERY COMMON CANDIDA TO SEE IN OR

–> massive doses of fluconazole to overcome resistance of Globrata (finicky)

does not cover: aspergillus, kruseie, mucor

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7
Q

Adverse effect of Fluconazole

A

Hepatotoxicity

Qtc prolongation

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8
Q

What is the DOC for Aspergillus?

adverese SE:?

A

Voriconazole

SE: DELIRIUM, HALLUCINATION

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9
Q

ISAVUCONAZOLE can be used for?

A

Aspergillus and Mucor

claim to fame: “azole” with shortened Qtc

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10
Q

Big things for Echinocandins

A

first-line agent for CANDIDA GLOBRATA

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11
Q

What are the samples of Echinocandins?

A

“Fungin”

Caspofungin

Micafungin – poor penetration of urine

Andulafungin

- first line for Candida Globrata -

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