HYPOXIC ISHEMIC ENCEPHALOPATHY Flashcards
AAP criteria to diagnose perinatal criteria / HIE
🌟Prolonged metabolic acidosis , pH <7 of Umbilical arterial blood sample
🌟persistence of APGAR score 0-3 for more than 5 min
🌟Signs of CNS dysfunction - seizures, hypotonia etc
🌟Signs of Multi organ dysfunction
Most common cause of Neonatal seizures
HIE
WHO DEFN of Birth Asphyxia
A baby who has failed to initiate or sustain breathing
APGAR score at 1 min is 4-7
NNF DEFN of Birth Asphyxia
National neonataology forum
APGAR score 0-3 at 1 min
Most sensitive structure to hypoxia
Neurons
Staging system used in HIE
Sarnat and sarnat
3 stages
Pattern of HIE in TERM baby
Parasagittal infarcts
Spastic quadriplegia
Selective cortical neuronal necrosis
Status marmoratus of basal ganglia and thalamus
Pattern of HIE in Preterm baby
Periventricular leuckomalacia
Periventricular white matter affected
Causes Spastic diplegia
Lower limb tone is more than upper limb selective sub cortical neuronal necrosis
Factors affecting area of brain involved
Gestational age
Metabolic demand of brain
Blood supply