HYPOXIC ISHEMIC ENCEPHALOPATHY Flashcards

1
Q

AAP criteria to diagnose perinatal criteria / HIE

A

🌟Prolonged metabolic acidosis , pH <7 of Umbilical arterial blood sample
🌟persistence of APGAR score 0-3 for more than 5 min
🌟Signs of CNS dysfunction - seizures, hypotonia etc
🌟Signs of Multi organ dysfunction

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2
Q

Most common cause of Neonatal seizures

A

HIE

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3
Q

WHO DEFN of Birth Asphyxia

A

A baby who has failed to initiate or sustain breathing
APGAR score at 1 min is 4-7

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4
Q

NNF DEFN of Birth Asphyxia

A

National neonataology forum

APGAR score 0-3 at 1 min

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5
Q

Most sensitive structure to hypoxia

A

Neurons

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6
Q

Staging system used in HIE

A

Sarnat and sarnat
3 stages

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7
Q

Pattern of HIE in TERM baby

A

Parasagittal infarcts
Spastic quadriplegia
Selective cortical neuronal necrosis
Status marmoratus of basal ganglia and thalamus

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8
Q

Pattern of HIE in Preterm baby

A

Periventricular leuckomalacia
Periventricular white matter affected
Causes Spastic diplegia
Lower limb tone is more than upper limb selective sub cortical neuronal necrosis

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9
Q

Factors affecting area of brain involved

A

Gestational age
Metabolic demand of brain
Blood supply

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