Hypothalamus and pituitary Flashcards
what are the anterior pituitary hormones?
thyroblobulin corticotropin gonadotropin prolactin growth hormone
which anterior pituitary hormones are absolutely necessary for human existence?
thyroglobulin
corticotropin
what are the vascular causes of hypopituitarism?
sheehan’s pospartum necrosis
diabetic peripartum necrosis
carotid aneurysm
which two anterior pituitary hormones do not have simple end organ feedback loops and are thus have the most commonly associated conditions?
prolactin
GH
what are the clinical manifestations of PL excess?
galactorrhea
hypogonadism
what are the clinical manifestations of GH excess?
acromegaly
gigantism
what is the cause of hypogonadism due to hyperprolacinemia?
due to inhibition of GnRH release form hypothalamus
what are the two complications of hyperprolactinemia?
hypogonadism
galactorrhea
which two antipsychotic drugs commonly cause hyperprolactinemia?
risperdone
halidol
what is the most common type of functional pituitary adenoma?
prolactinoma
what is the treatment for a small, symptomatic prolactinoma?
bromocriptine (dopamine agonist)
what is the treatment for a large prolactinoma?
bromocriptine
tamoxifen
transphenoidal resection
radiation
what is the main symptom of hypoprolactinemia?
failure to lactate
what are the lab results of GH excess?
hyperglycemia hypercalcuria hypercalcemia hyperphosphatemia hyperprolactinemia
