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AN4017 > Hypothalamic Neurogenesis > Flashcards

Hypothalamic Neurogenesis Flashcards

1
Q

Lateral hypothalamic nucleus

A

Arousal
Feeding
Reward

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2
Q

Arcuate Nucleus

A

Energy balance
Reproduction
GH release
- neuroendocrine signals
- behavioural responses to food

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3
Q

Ventromedial hypothalamic nucleus

A

Energy balance
Glucose metabolism
Sex-specific behaviours

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4
Q

Mammillary body

A

Learning and memory
Key in limbic system

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5
Q

Lateral hypothalamus manipulation

A

Feeding centre
- stimulation - hyperphagia, obesity
- lesions - anorexia

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6
Q

VMH manipulation

A

Satiety centre
- lesions cause hyperphagia

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7
Q

AgRP/NPY & POMC Neurons

A

Project from ARC -> PVN
- controls food intake and energy balance

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8
Q

What influences signalling from AgRP/NPY & POMC Neurons

A
  • leptin
  • Glucocorticoids
  • Insulin
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9
Q

AC1 cells

A
  • NPC population in hypothalamus
  • express SOX2 and Nestin
  • generate mature hypothalamic neurons
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10
Q

Tanycyte express what TFs?

A
  • RAX
  • LIM/LHX2
  • SOX2
  • SOX9`
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AN4017 (5 decks)

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