Hypothalamic and anterior pituitary hormone related disorders

Question 1

What are the six key hormones released by the anterior pituitary?

Answer 1

Thyroid-stimulating hormone (TSH)

adrenocorticotropic hormone (ACTH)

follicle-stimulating hormone (FSH)

luteinising hormone (LH)

growth hormone (GH)

prolactin (PRL)

Question 2

What does ACTH (corticotropin) stimulate?

Answer 2

The adrenal cortex to produce corticosteroids, mainly glucocorticoids and some androgens.

Question 3

What is tetracosactide used for?

Answer 3

To test adrenocortical function (diagnosing adrenal insufficiency).

Question 4

What are gonadotrophins?

Answer 4

Hormones secreted by the pituitary that stimulate the gonads (e.g., FSH, LH, hCG).

Question 5

What are FSH and LH used for in women?

Answer 5

Treating infertility.

Question 6

What is somatropin?

Answer 6

Recombinant human growth hormone used in adults and children.

Question 7

What does gonadorelin do when injected IV?

Answer 7

Causes a rapid rise in LH and FSH levels.

Question 8

What are gonadorelin analogues used to treat?

Answer 8

Endometriosis, infertility, breast cancer, and prostate cancer.