Hypoparathyroidism Flashcards
1
Q
What is the presentation of Hypoparathyroidism? SPASMODIC
A
Low Ca2+ causes S - Spasms P - Perioral paraesthesia A - Anxiety, Irritability S - Seizures M - Increased muscle tone - Wheeze, Colic, Dysphagia O - Orientation impairment eg confusion D - Dermatitis I - Impetigo herpetitformis C - Cardiomyopathy
2
Q
What are the causes of Hypoparathyroidism?
A
Autoimmune
Congenital: DiGeorge syndrome
Iatrogenic - Surgery, Radiation
3
Q
What are the features of DiGeorge syndrome?
A
Cardiac abnormality: Fallot’s Abnormal facies Thymic aplasia Cleft palate Hypocalcaemia Chr 22 defect
4
Q
What is the treatment of Hypoparathyroidism?
A
Ca supplements
Calcitriol
5
Q
What investigations can be done in a patient with suspected Hypoparathyroidism?
A
↓Ca
↑PO4
↓PTH
6
Q
What is Pseudohypoparathyroidism?
A
Failure of a target organ to respond to PTH causing symptoms of hypocalcaemia
Treat with Ca2+ and Calcitriol
