Hypogonadism/ Androgen Deficiency

Question 1

What are some potential causes of androgen deficiency?

Answer 1

genetic disorders eg Kleinfelter syndrome, disorder of the testis (primary damage or hypergonadotropic hypogonadism), disorders of the pituitary and hypothalamus, androgen receptor defects causing androgen insensitivity

Question 2

What are clinical features of androgen deficiency

Answer 2

increased fatigue and weakness, sexual dysfunction, mental problems (low mood, irritability, depression), obesity and osteoporosis

Question 3

How is androgen deficiency diagnosed?

Answer 3

at least 2 tests of serum testosterone and luteinising hormone or different days