hyperthyroidism

Question 1

Hyperthyroidism

Answer 1

Increased T3 and T4 , decreased TSH

Question 2

most common case of hyperthyroidism

Answer 2

Graves’ disease (TSH receptor
antibodies )

Question 3

If uncontrolled hyperthyroidism , it is associated with ;

Answer 3

• Pre-eclampsia ( the most common) in mother
• increased spontaneous abortion
• prematurity
• intrauterine growth retardation (IUGR)(most common in fetus)
• Thyroid storm is a life-threatening hypermetabolic state presenting with pyrexia, tachycardia, and severe dehydration.

Question 4

Management for uncontrolled Hyperthyroidism

Answer 4

propylthiouracil (PTU), β-blocking agents, steroids, and iodine.

Question 5

Hyperthyroidism Clinical features

Answer 5

1. Tachycardia
2. Thyromegaly
3. Exophthalmos
4. inadequate weight gain or even
   weight loss
5. elevated total and free T4,
   decreased TSH

Question 6

Hyperthyroidism Treatment

Answer 6

1st Trimester PTU,2nd and 3rd
Trimester Methamazole

Question 7

maternal complications

Answer 7

**placental abruption (most common)
* abortion
* pregnancy induced hypertension
*preterm delivery
*anemia
*higher susceptibility to infection

**in untreated cases : cardiac arrythmias,congestive heart failure,thyroid storm

Question 8

fetal complications

Answer 8

**IUGR (most common)
*fetal neonatal hyperthyroidism
*stillbirth
*prematurity
*morbidity related to antithyroid medications
*miscarriage
*preterm labour