Hyperthroidism Pre-Op Flashcards

A 38-year-old lady going for surgery. Pre-op bloods showed. High T3, high T4, low TSH

1
Q

A 38-year-old lady going for surgery. Pre-op bloods showed. High T3, high T4, low TSH
Q1. Diagnosis?

A

Hyperthyroidism

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2
Q

Q2. What are the causes of hyperthyroidism?

A

Most probably is idiopathic,
It could be due to goiter, inflammation like Hashimoto’s in early stages, adenoma of thyroid, viral infection, central due to hypersecreations form pituitary gland

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3
Q

Q5. What are the functions of thyroxine (T4)?

A

Heart –> chronotropic and inotropic
Adipose tissue – > catabolic (lipolysis)
Muscles – > catabolic (ms break down)
Bone – > developmental
CNS – > developmental
Gut – > metabolic
Lipoprotein – > metabolic

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4
Q

Q6. What are the possible complications if patient went to surgery without
correction?

A

Thyroid storm
MI

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5
Q

Q7. What are the anaesthetic considerations?

A

Thyroid storm.
AF
HIGH RISK KF OF MI

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6
Q

Given this ECG :-

Q8. Diagnosis?

A

ABSENT P WAVE AND IRREGULAR PUSLE SO AF

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7
Q

Q9. What are the clinical picture of thyroid crisis (storm)?

A

Dehydration
Hyper pyrexia
AF
Restlessness
Hyperglycemia
Confusion
Could lead to Mi
Q10. Management?

CCRISP
O2 - IV fluids - cooling and ice packs – diuretics for cardiac failure – Digoxin in uncontrolled AF – Sedation – IV hydrocortisone
Definitive – > Carbimazole / Lugol’s iodine / propranolol IV 1-2 MG
OR ORAL 40 MG 6HRLY
May give ACEI

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8
Q

Q10. Management?

A

CCRISP
O2 - IV fluids - cooling and ice packs – diuretics for cardiac failure – Digoxin in uncontrolled AF – Sedation – IV hydrocortisone
Definitive – > Carbimazole / Lugol’s iodine / propranolol IV 1-2 MG
OR ORAL 40 MG 6HRLY
May give ACEI

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9
Q

Q11. What is Lugol’s Iodine? How does it act? How does the radioactive iodine act?

A

Aqueous iodine in form of potassium iodide and iodine in water
- Inhibit thyroid hormones synthesis and conversion. / Decrease vascularity and inhibit iodine binding.
Cannot use for long term
- radioactive iodine – destroy thyroid tissue and leading to decrease thyroid hormones

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10
Q

Q12. Where to manage patient?

A

ITU

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