Hypertensive Medication Flashcards
Examples of ACE inhibitors
Captopril
Enalapril
Lisinopril
Ramipril
ACE Inhibitors: Mechanism of Action
Cause inhibition of ACE levels, reducing angiotensin II and aldosterone levels and increasing bradykinin levels
ACE Inhibitors effect:
Vasodilation
Reduction in peripheral resistance
Little change in CO and HR
Reduced sodium retention
ACE inhibitor Route of Administration
Oral
ACE inhibitors indication
Hypertension
Heart Failure
Renal dysfunction
ACE inhibitors Adverse Effects
Characteristic cough Hypotension Dizziness Headache Diarrhoea Muscle Cramps
ACE Inhibitors Contraindication
Pregnancy
Renovascular disease
Aortic stenosis
ACE inhibitor + NSAIDs
Hypotension
Angiotensin II receptor antagonists examples
Losartan
Valsartan
Irbesartan
Angiotensin II receptor antagonists mechanism of action
Inhibit the Angiotensin II receptor
Angiotensin II receptor antagonists Effects
Vasodilation
Reduction in peripheral resistance
Angiotensin II receptor antagonists Route of administration
Oral
Angiotensin II receptor antagonists indication
Hypertension
Angiotensin II receptor antagonists Contraindications
Pregnancy
Breastfeeding
Caution in renal artery stenosis and aortic stenosis
Angiotensin II receptor antagonists adverse effects
Cough Orthostatic hypotension Dizziness Headache Fatigue Hyperkalaemia Rash