Hypertension part II Flashcards

1
Q

First-line medications for HTN

A

ACE
ARBs
CCB
Thiazides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

After getting dx with HTN stage 1, what should you do?

A

Order a lipid panel in order to see if they have an ASCVD > 10% to treat

After 2 readings (for textbook medicine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How long does it take BP meds to take affect?

A

4-6 week intervals
Can counsel about at-home cuff (reliable, cross-checked

Want to see if the reading is less than 130/80 to make sure that the treatment is working, and if it is less than 100/60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

If a patient has CKD, what should you be mindful of when treating HTN? What do you do for this?

A

Potassium status

BMP to check kidney function that there is not a jump

Can get renal artery stenosis and order an ultrasound to dx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What patients should specifically be on an ACE or an ARB?

A

DM
CKD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What meds should you start with for HTN?

A

Any of them
ACE/ARB should not be taken at the same time though!
CCB
Thiazide

Pick one med, max it out, then pick another, max it out, then pick it out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When do we use BB?

A

After you max meds out, or if there is a heart issue

Aldosterone antagonist should not be started as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What should you keep in mind with comorbid treatment and treating HTN?

A

Could kill two birds with one stone and may be able to treat multiple conditions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

After a patient is stable (130/80), how often should you see a patient?

A

every 6-12 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How often should you do an EKG for HTN patients?

A

2-4 years, unless there is additional concerns.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What additional labs can you order for HTN patients?

A

Lipids
TSH
UA (make sure kidney is ok)

Don’t have to

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the two different types of hypertensive crises?

A

Hypertensive urgency
Hypertensive emergency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is Hypertensive urgency and
Hypertensive emergency treated?

A

Urgency = outpatient
Emergency = inpatient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is hypertensive urgency? What is the BP?

A

Severe HTN w/out ACUTE symptoms
BP > 220/125 mmHg¹

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the etiology of HTN urgency?

A

Exacerbation of poorly controlled chronic HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are red flags of a HTN urgency that would merit a referral to inpatient treatment?

A

HA
No urine
Neurologic issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What labs should you obtain for HTN urgency?

A

BMP, UA, and EKG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is a short-acting HTN treatment that is used for ACUTE treatment only?

A

Clonidine (very small pill)
Great for fast-acting HTN Urgency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the first thing that you should ask a patient in a HTN urgency?

A

Taken meds? Can call pharmacy to see if they have been picking up meds.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the overall goal of HTN urgency treatment?

A

Reduce BP w/in hours!
Should still start low and go slow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are the four in-office agents for HTN urgency?

A

Clonidine
Captopril (ACE-I)
Metoprolol tartrate (short-acting)
Hydralazine (Dosed 3 times a day)

Most (metoprolol)
Common (clonidine)
Cure (captopril)
Hypertension (Hydralazine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is a concern of clonodine?

A

Sedation (clon = clause = santa = sleep)

Worry about driving

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is a concern of captopril?

A

Excessive hypotension
Worried about

24
Q

What is a concern of metoprolol tartrate?

A

bradycardia

25
Q

Why do you see tachycardia in hydralazine?

A

Vasodilation, which reduces BP, but requires the heart to pump faster

26
Q

What is nifedipine and why is it no longer used?

A

CCB
Response is unpredictable

27
Q

What differs HTN Emergency from Urgency?

A

NOT the number, just that there is organ failure

28
Q

What should you do for HTN Emergency first?

A

EMS referral with nitroglycerine or clonidine

29
Q

What PE should you check for HTN emergency?

A

Head to toe, but need to treat right away

30
Q

Why do you keep BP elevated for ischemic stroke?

A

Reducing blood flow can further organ damage

31
Q

What BP should you do for someone who is actively bleeding?

A

Lower BP to reduce bleeding

32
Q

What do you do for the initial evaluation of HTN emergency?

A

Same as HTN

33
Q

Why do you do a CXR for HTN emergency?

A

CXR allows you to check for HF, aortic dissection,

34
Q

Why do you order a urinary drug screening for HTN emergency?

A

Cocaine can elevate BP

35
Q

What labs do you order for HTN emergency?

A

CBC, CMP, EKG CXR, CT head (w/o 1st), UA, UDS, and so on

36
Q

Why no contrast for HTN emergency?

A

Worsens hemmoragic stroke

37
Q

What type of therapy do you do for a HTN emergency and how quickly do you lower BP and why?

A

Parenteral therapy should be used
Lower BP by no more than 25% in first 2 hours¹ (not more than this so that you maintain O2 delivery to other tissues)

38
Q

What is the end BP goal of a HTN emergency?

A

Then goal BP of 160/100 over next 2-6 hours

39
Q

What are the specific goals of BP for HTN Emergency for Ischemic CVA, Hemorrhagic CVA, Aortic dissection, and MI?

A

Ischemic CVA - SBP between 180-200 mmHg with slow reduction
Hemorrhagic CVA - target SBP is <140 mmHg
Aortic Dissection - goal SBP <120 mmHg
MI - will need anticoagulation and oxygen; typically use NTG for BP reduction, but no set goal

40
Q

What 2 med classes do you use for HTN emergency?

A

Beta blockers
Calcium channel blockers

41
Q

What are the 4 preferred HTN emergency meds in order of preference?

A

Nicardipine (CCB)
Clevidipine (CCB)
Labetalol (BB)
Esmolol (BB)
Fenoldopam (dopamine receptor agonist, rarely used)

42
Q

If BP is still not managed with the 4 preferred HTN emergency meds, what other meds do you use?

A

Enalaprilat
Furosemide
Nitroglycerine
Nitroprusside (should not be used!)

43
Q

What happens to your CO and HR during pregnancy? What is an abnormal BP>

A

Both increase
CO increases by 40%
HR increases 10 bpm

Abnormal BP is >140/90

44
Q

How does dx of HTN different in preggos?

A

Diagnosis requires two elevated readings at least 4 hours apart

45
Q

What is preeclampsia?

A

new onset HTN (BP ≥ 140/90) and proteinuria (24h urinary protein >300 mg/24h or creatinine ratio ≥0.3) after 20 weeks gestation

46
Q

What is the difference between preeclampsia and eclampsia?

A

eclampsia includes seizures as well as the other characteristics of preeclampsia.

47
Q

What is gestational HTN?

A

HTN (BP ≥ 140/90) after 20 weeks gestation w/o pre-existing HTN or proteinuria

48
Q

What med classes are CI in gestational or chronic HTN in pregnancy?

A

ACE and ARBs!

49
Q

What medications do you use for Acute BP treatment?

A

IV labetalol
IV hydralazine
oral immediate-release nifedipine

50
Q

What medications do you use for chronic BP treatment?

A

labetalol
ER nifedipine
methyldopa

51
Q

What is the target BP for preggos w/ HTN?

A

Target BP = 130-150/80-100
NOT recommended to reduce BP by more than 25% over 2 hours

52
Q

Define resistant HTN?

A

Defined as the failure to reach BP control in patients who are adherent to full doses of an appropriate 3-drug regimen, including a diuretic

53
Q

MC of resistant HTN?

A

Noncompliance with meds (because you are maxing out 3 meds)

54
Q

How do you manage resistant HTN?

A

Refer to nephro (preferred) or cardio to make adjustments

55
Q

What can you switch a patient on for resistant HTN?

A

Consider switching diuretic to aldosterone receptor blocker (spironolactone)

56
Q

Other than non-compliance, what can cause Resistant HTN?

A

Improper BP measurements
Volume overload and pseudotolerance
Poor lifestyle
Obesity
Alcohol
Drug-induced

57
Q
A