Hypertension Case Studies - Malcom Flashcards
When not contraindicated, what is often the first line pharmacological treatment of EH?
A thiazide diuretic, such as hydrochlorothiazide (HCTZ.)
After a hypersensitivity reaction to an ACE inhibitor, can another ACEI be prescribed instead? What about an ARB?
No and no. Other ACEIs and all ARBs are contraindicated once a pt has a hypersensitivity rxn to an ACEI.
What medication is often infused to lower BP during a hypertensive crisis?
During a hypertensive crisis, how quickly should blood pressure be lowered?
Nitroprusside
Quickly but not TOO quickly. Titrate the drug over a few minutes - don’t inject it all at once.
What serious side effect is possible with nitroprusside treatment?
How can this side effect be treated?
Cyanide poisoning (cyanide is a metabolic breakdown product of the drug)
Cease nitroprusside therapy, treat with sodium thiocyanate to metabolize the cyanide. Follow up with close observation.
What drug can be given specifically to African American pts with CHF?
Isosorbide dinitrate / hydralazine combo.
