Hypersomatotropism (Acromegaly) Flashcards
0
Q
Hypersomatotropism
Signalment
A
Senior cats
Rare in dogs - associated with estrous cycle, progesterone therapy, mammary gland carcinoma
1
Q
Hypersomatotropism
Pathophysiology
A
Benign functional tumor of the pituitary gland that releases excess growth hormone.
GH is a natural insulin antagonist.
2
Q
Hypersomatotropism
Clinical Signs/Physical Exam
A
PU/PD, polyphagia, wt loss, diabetic neuropathy
Can also have abnormal growth in an adult (wt gain, organomegaly, increased skull size)
3
Q
Hypersomatotropism
Diagnostics
A
GH levels
IgF-1 levels
MRI
4
Q
Hypersomatotropism
Treatment
A
Radiation
High doses of insulin
GH inhibitors
Spay dogs
5
Q
Hypersomatotropism
Prognosis
A
Poor
Due to weight loss and malnutrition
