Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

IMMUNOLOGY AND SEROLOGY > HYPERSENSITIVTY > Flashcards

HYPERSENSITIVTY Flashcards

1
Q

it is an exaggerated response to a harmless antigen that results in injury t the tissue, disease, or even death

A

Hypersensitivity reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

antigens that triggers type 1 hypersensitivity

A

Allergen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

type of hypersensitivity reaction that has complement involvement

A

Type 2 and type 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

t/f

Type 1 hypersensitivity requires 2 exposures to the allergen

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

examples of type 1 hypersensitivty

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

examples for type 2 hypersensitivity

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

examples for type 3 hypersensitivity

A

dengue
farmers lungs
—-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

characterized by severe itching, erythema, caused by localized vasodilation, leakage of fluid into the surrounding area, and a spreading area of reddness

A

Urticaria/ hives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

“panting” or breathlessness” caused by inhalation of small particles such as pollen, dust, or fumes

A

asthma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

laboratory testing for type 1 hypersensitivity

A

-in vivo skin test
>cutaneous and intradermal
-in vitro test
>rist
>rast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a competitive RIA test for Total IgE

A

Rist (radio immunosorbent test)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

a non-competitive RIA test for specific IgE

A

RAST (radio allergosorbent test)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

test for type II hypersensitivity

A

DAT
IAT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

examples of B cell deficiency

A

-transient hypogammaglobulinemia of infancy
-selective IgA = most common immunodeficiency
-burtons x-linked
-hyper Igm
-Hyper IgE
-isolated IgG subclass deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Immunodeficiency relating to T cells

A

-DiGeorge syndrome
-purine neucleoside phosphorylase deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Immunodeficiencies of combined B and T cells

A

-severe combined immunodeficiency
-bare lymphocyte
-x linked-scid
-adenosine deaminase
-wiskot-aldrich
-ataxia telangeictasia

17
Q

immunodeficiencies of phagocytic function

A

-CGD
-chediak- higashi
-leukocyte adhesion

18
Q

absence of BTK gene (burton’s tyrosine kinase
-immature B cells will not mature because of lack of enzyme

A

Burton’s X-linked agammaglobulinemia

19
Q

-failure of mature B cells to become plasma cells
-decrease IgA and IgG

A

Common Variable Immunodeficiency
(CVI)

20
Q

-failure of B cells to produce antibodies due to delayed maturation of thymus
-aslo referred to ad Pediatric hypogammaglobulinemia

A

Transient Hypoagammaglobulinemia

21
Q

CD40 present on the surface of B cells will react with CD40 ligand on T helper cells to initiate class switching of IgM to IgG

A

IgM- IgG switching

22
Q

Increase levels of IgM
-absence of CD40 ligand on T helper Cell

A

X-linked Hyper IgM syndrome

23
Q

impaired IL-2 production
-hyperactive Th2
-prone to allergic reaction

A

Hyper IgE

24
Q

-most common primary immunodeficiency
-failure of B cell to become IgA-producing plasma cells

A

IgA deficiency

25
Q

-Person lacking a specific IgG subclass
-vulnerable to certain kinds of infection

A

Isolated IgG subclass deficiency

26
Q

a developmental abnormality of the third and fourth pharyngeal pouches that affects thymic development
-absence of chromosome 22q

A

DiGeorge Synrome/anomaly

27
Q

-accumulation of deoxyguanosine triphosphate which is toxic to immature T lymphocytes in the thymus

A

Purine-nucleoside phosphorylase deficiency

28
Q

Abnormality in integral membrane (CD43); gene responsible for defect
TRIAD of WAS
-eczema
-thrombocytopenia
-immunodeficiency

A

Wiskott-Aldrich Syndrome

29
Q

-aka louis-bar syndrome is a neurodegenerative inherited disorder
-absence of ATS gene which codes for ATM protein

A

Ataxia- Telangiectasia Syndrome

30
Q

Absence of NADPH oxidase

A

Chronic granulomatous Disease

31
Q

Absence of LYST gene (lysosomal trafficking) which codes for LYST protein
-albinism: transport of melanin to melanocytes fail

A

Chediak-Higashi syndrome

32
Q

HLA associate with Systemic Lupus Erythematosus

A

HLA-DR2
HLA- DR3

33
Q

HLA associate with Rheumatoid Arthritis

A

HLA-DR1
HLA-DR4

34
Q

HLA associate with Hashimoto’s thyroiditis

A

HLA-DR4
HLA- DR5

IMMUNOLOGY AND SEROLOGY (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions