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Immunology > Hypersensitivity reactions > Flashcards

Hypersensitivity reactions Flashcards

1
Q

What causes a type 1 hypersensitivity reaction?

A

IgE causing mast cell degranulation

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2
Q

Which conditions are examples of a type 1 hypersensitivity reaction?

A

Anaphylaxis, eczema, asthma, hayfever

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3
Q

What kind of hypersensitivity reaction is anaphylaxis?

A

Type 1

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4
Q

What causes a type 2 hypersensitivity reaction?

A

Antibody dependent - complement mediated i.e. IgG or IgM triggers the classical pathway of the complement system

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5
Q

Which conditions are examples of a type 2 hypersensitivity reaction?

A

Transfusion reaction, haemolytic disease of the newborn, pernicious anaemia, Grave’s disease, myasthenia gravis

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6
Q

Which type of hypersensitivity reaction is haemolytic disease of the newborn?

A

Type 2

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7
Q

Which type of hypersensitivity reaction is myasthenia gravis?

A

Type 2

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8
Q

Which type of hypersensitivity reaction is pernicious anaemia?

A

Type 2

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9
Q

Which type of hypersensitivity reaction is a transfusion reaction?

A

Type 2

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10
Q

What causes a type 3 hypersensitivity reaction?

A

Immune complex mediated

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11
Q

Which conditions are examples of a type 3 hypersensitivity reaction?

A

Rheumatoid arthritis, SLE, viral hepatitis, glomerulonephritis

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12
Q

Which type of hypersensitivity reaction is viral hepatitis?

A

Type 3

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13
Q

Which type of hypersensitivity reaction is rheumatoid arthritis?

A

Type 3

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14
Q

Which type of hypersensitivity reaction is glomerulonephritis?

A

Type 3

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15
Q

Which type of hypersensitivity reaction is SLE?

A

Type 3

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16
Q

Which type of hypersensitivity reaction is a Mantoux test?

A

Type 4

17
Q

Which type of hypersensitivity reaction is contact dermatitis?

A

Type 4

18
Q

Which type of hypersensitivity reaction is Graft vs. host rejection?

A

Type 4

19
Q

What is the cause of a type 4 hypersensitivity reaction?

A

T cell mediated, delayed, hypersensitivity reaction.

20
Q

What are examples of a type 4 hypersensitivity reaction?

A

Contact dermatitis, Mantoux test, graft vs. host disease

Immunology (6 decks)

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