Hypersensitivity

Question 1

Define Hypersensitivity

Answer 1

1. Disorders caused by immune responses
2. Injurious (tissue injury and disease) or pathologic immune reactions

Question 2

What term describes a reflection of excessive or aberrant immune responses

Answer 2

Hypersensitivity

Question 3

List the 2 ways (situations) hypersensitivity reactions may occur

Answer 3

1. Responses to foreign antigens may be uncontrolled resulting in tissue injury
2. Immune responses may be directed against self antigens, as a result of failure of self tolerance

Question 4

Define:
1. Autoimmunity
2. Autoimmune diseases

Answer 4

1. Responses against self antigens
2. Disorders caused by Autoimmunity

Question 5

How are hypersensitivity reactions classified

Answer 5

On the basis of the principal immunological mechanism that is responsible for tissue injury and disease

Question 6

List the four types of hypersensitivity

Answer 6

1. Type I (Immediate hypersensitivity)
2. Type II (Antibody mediated diseases)
3. Type III ( immune complex mediated diseases)
4. Type IV (T-cell mediated diseases)