Hyperpituitarism: Surgical and Pharmacological Management

Question 1

Hyperpituitarism: Pharmacological Management

Answer 1

1. Bromocriptine (Parlodel)
2. Octreotide and Lanreotide (Somastatin analog)

Question 2

Hyperpituitarism: Surgical Management

Treatment of choice

Answer 2

Hypophysectomy

Question 3

Hyperpituitarism: Pharmacological Management

Lowers GH level and prolactin level

Answer 3

Bromocriptine (Parlodel)

Question 4

Hyperpituitarism: Pharmacological Management

Use pre-operatively to improve pt condition and shrink the tumor

Answer 4

Octreotide and Lanreotide (somastatin analog)

Question 5

Partial or complete removal of the pituitary gland

Answer 5

Hypophysectomy

Question 6

Hypophysectomy

Indications for surgery

Answer 6

1. Pituitary tumors
2. Diabetic retinopathy
3. Metastatic cancer of breast or prostate

Question 7

Hypophysectomy

Surgical approaches

Answer 7

Craniotomy - transfrontal

Transsphenoidal - incision via inner aspect of upper lip and gingiva

Question 8

Nursing Interventions after Transsphenoidal Hypophysectomy

Answer 8

1. Keep head elevated to promote venous drainage for 2 weeks
2. Maintain nasal pack as per doctor’s order
3. Provide good oral care
4. Avoid blowing of nose and other activities that increase ICP
5. Report output greater than 900ml/2hrs (potential risk for D.I.)