Hyperlipidaemia

Question 1

Name examples of drugs within the statins drug class

Answer 1

1. Atorvastatin
2. Rosuvastatin
3. Simvastatin

Question 2

Describe the statins mechanism of action

Answer 2

1. Statins work by inhibiting an enzyme called HMG-CoA reductase (plays in a key role in production of cholesterol)
2. This lowers LDL in the blood
3. Decreases risk of plaque buildup

Question 3

Drug class of ezetimibe ?

Answer 3

Cholesterol absorbing inhibitors

Question 4

Describe the mechanism of action for cholesterol absorbing inhibitors

Answer 4

1. Works by inhibiting the absorption of cholesterol in the small intestine
2. Does this by blocking a protein called NPC1L1
3. reducing cholesterol absorption causes lower levels of LDL in the blood