hyperglycemic crisis 2 Flashcards

1
Q

how often should blood glucose be monitored to prevent hypoglycemia

A

every 1-2 hours

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2
Q

how is hyperchloremic metabolic acidosis avoided

A

switch fluid to half normal NS when rehydrated

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3
Q

what can occur is blood glucose is decreased too quickly

A

cerebral edema

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4
Q

hyperglycemia is associated with worse outcomes, including:

A
  1. impaired wound healing
  2. increased infection rates
  3. increased mortality in certain patients
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5
Q

glucose production occurs via what?

A

gluconeogenesis and glycogenolysis

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6
Q

what is the metabolic effect of cortisol

A

increased gluconeogenesis

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7
Q

what was the first land mark trial that looked at glucose in critically ill patients

A

leuven surgical trial

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8
Q

what wre the results of the Leuven medical trial

A

intensive insulin therapy reduced morbidity but not mortality among all patients in medical ICU

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9
Q

what were the results of the NICE_SUGAR study

A

intensive glucose control (81-108) increased mortality in ICU; target of 180 reduced mortality

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10
Q

what is the best target blood glucose in the ICU

A

140-180

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11
Q

what is systemic vascular resistance

A

resistance of flow of blood in the peripheral arterial vessels

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12
Q

what is the term for the stretched condition of the heart muscle at the end of diastole

A

preload

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13
Q

what is the term for the force against which the ventricle contracts that is contributed to by SVR

A

afterload

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14
Q

what is the term for the volume of blood ejected from the left side of the heart in 1 minute

A

cardiac output

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15
Q

what is mean arterial pressure

A

average pressure in an artery over a cardiac cycle

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16
Q

what characterizes the physiologic state of “shock”

A

significant reduction in tissue perfusion

17
Q

what determines systemic tissue perfusion

A

cardiac output and systemic vascular resistance

18
Q

what does HR + SV =?

A

CO

19
Q

what does MAP/CO =?

A

SVR

20
Q

what physiological features are determined by SVR?

A

vessel length
blood viscosity
vessel diameter