Hunger and satiety

Question 1

satiety center

Answer 1

VMN and PVN

Question 2

hunger center

Answer 2

lateral hypothalamus

Question 3

NPY

Answer 3

released to increase appetite with AgRP

pathway stimulated by Ghrelin

stimulates desire for food and motor drive for food

Question 4

insulin

Answer 4

can cross BBB to stimulate hypothalamus

REDUCES FOOD INTAKE by acting on the melanocortin pathway

Question 5

Leptin

Answer 5

released from adipose, crosses BBB
stimulates melanocortin pathway and inhibits NPT/AgRP

decreases appetite

leptin resistance is responsible for some obesity

Question 6

CCK

Answer 6

potentiates the effects of leptin after being released in the duo after a high fat meal

Question 7

Peptide YY

Answer 7

promotes short term satiety

binds Y2 receptor of the hypothalamus
inhibits NPY and stimulates POMC

low in OB

Question 8

Ghrelin

Answer 8

secreted by oxyntic glands of the stomach in response to fasting

increases appetite

low in OB

stimulates NPY pathway

Question 9

Melanocortin pathway

Answer 9

appetite inhibiting neurons containing POMC

insulin, leptin, and CCK stimulate