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HDM Cards > Humoral Immunity > Flashcards

Humoral Immunity Flashcards

1
Q

IgM class switch signal

A

Nothing!

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2
Q

IgE class switch signal

A

IL4 from Th2 and IL4+ Tfh

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3
Q

IgG class switch signal

A

IFNgamma from Th1

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4
Q

IgA class switch signal

A

TGFbeta from Treg and Macrophages

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5
Q

Lymphoma

A

Starts in germinal centers
Ig gene mutation can incorporate oncogenes or
make self reactive B cells

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6
Q

MASP1 Action

A

Binds MBL, MASP2 and MASP3

Activates MASP3

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7
Q

MASP2 Action

A

Binds Lectins

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8
Q

MASP3 Action

A

Cleaves C4

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HDM Cards (6 decks)

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