General Deck Flashcards
TLR1/2 Heterodimer
Recognizes Lipoproteins, GPI
On: Monocytes, DC’s Eosinophils, Basophils and Mast Cells
TLR2/6 Heterodimer
Recognizes Lipoteichoic acid, Zymosan
On: Monocytes, DC’s Eosinophils, Basophils and Mast Cells
TLR3
Recognizes DSvDNA
On: NK Cells
TLR4 homodimer
Recognizes lipopolysaccharide
On: Macrophages, DC’s, Mast Cells, Eosinophils
TLR5
Recognizes flagellin
On: Intestinal Epithelium
TLR7
Recognizes SSvRNA
On: Plasmacytoid DC’s, NK Cells, Eosinophils, B Cells
TLR8
Recognizes SSvRNA
On: NK Cells
TLR9
Recognizes unmethylated CpG-rich DNA
On: Plasmacytoid DC’s, B cells, Eosinophils
IgA
Dimer Structure
In mucosa
Highest amount in the body
IgD
Monomer Structure
Ag receptor on Naive B cells
IgE
Monomer Structure
Defend against parasites and allergy hypersensitivity
IgG
Monomer Structure
Opsonize, Activate complement, High affinity
Highest amount in blood
IgM
Pentamer Structure
Ag receptor on Naive B cells, activate complement
Have low affinity but high avidity
