Human Science NEURO Flashcards
Parkinson’s
Who is affected
40year old +
0.3%
Parkinson’s
Where in brain ?
Basoganglia (substantial niagra)
Parkinson’s
Main features (4)
Tremor
Rigidity
Postural instability
Bradykanesia (slow movement)
Parkinson’s
Risk factors
Age
Gender (men)
Genetics (family)
Smoking
Coffee
Head trauma
Parkinson’s
Transformation of signals
- Cerebral cortex into basognaglia
- Basoganglia back to cerebral cortex (through thalamus)
- Cerebral correct to spinal cord to get to muscles
Parkinson’s
What’s the problem and where/why
Not enough dopamine produced within substantial niagra. (As it deteriorates)
Dopamine act as a neurotransmitter.
Dopamine doesn’t bind to the receptors.
Thalamus struggles to send signals to the cerebral cortex.
Therefore movement not coordinated or controlled
Parkinson’s
Treatment/ management
Medication (levadopa)
Increase or substitution of dopamine
Surgery- electrodes in brain.
Physio- balance, flexibility, strength,
Gait- stepping strategies, cuing, dual task
To reduce falls and improve mobility
MS
What is it
Auto immune disease that targets myelin and oligodendrocytes
Ms
What creates the myelin
Oligodendrocytes
Ms
What does myelin do
Acts as a thermal around the axon to allow smooth conduction of signals
Ms
Cause and risk factors
No cause - idiopathic
Genetics- female
Environment - vitD
Ms
Types of ms
Relapse remitting (90%)
Relapse progressive
Primary progressive
Secondary progressive
Ms
Symptoms
(Charcot Neuro triad)
Tremor (weakness, spasms, coordination)
Dysarthria (speech, swallow/ eating)
Nystagmus (rapid eye movement, loss/ double)
Ms
What targets the demyelination
T-cells attack myelin and oligodendrocytes
Stroke
Signs/ symptoms
F
A
S
T
Balance, dizziness, headache, numbness/wrakness
50% experience central post stroke pain: burning, shooting, spasticity & depression