Human Science CVR Flashcards
Bronchiectasis
What is it
Bronchi are dilated and are filled with mucus that narrows the airway
Bronchiectasis
Why does it happen
Typically due to previous infection or anything damaging the bronchi . (Pneumonia, whooping cough). (Cystic fibrosis - sticky mucus production)
Or problem with immune system.
No obvious cause: idiopathic
Bronchiectasis
What happens with the bronchi wall
Epithelium is a barrier of cells to resist infection. Includes goblet cells that forms mucus to trap bacteria. The mucocillary escalators then move the sputum up the airway to remove bacteria.
Damage to epithelium= damage to cell wall = mucocillary escalator gets impaired and can’t transport bacteria out causing infection and possibly permanent airway Remodelling.
Bronchiectasis
Symptoms
Chronic cough
Recurring lung infection
SOB
Wheezing
Fatigue
Chest pain
Bronchiectasis
Treatment
Chest vibrations/ percussion
Postural drainage
Bronchodilators (inhaler)
Antibiotics = infection
Hydration
Active cycle breathing technique (ACBT)
Positive / negative pressure devices
Chronic bronchitis
What is it and diagnosis
Repetition of irritating the bronchials causing them to inflame and damaging the cilia causing impairments and build up of mucus/ bacteria = infection.
Cough everyday for 3+months for 2years (with sputum)
Emphysema
What is it
Swelling of alveoli.
Alveoli gets damaged and looses its elasticity and permanently enlarges which makes it hard to push air out and causes air trapping/ dead space
COPD
Symptoms
FVC (forced vital capacity) ⬇️due to air trapping (max air exhaled)
FEV1 (forced expiratory volume in 1sec) ⬇️
Poor gas exchange = parcel pressure of co2 in lungs⬆️ = Hypercapnia
⬇️O2 in blood = hypoxia
Wheezing
Crackles
Lung infection
Dyspnea - SOB
Hyper-inflated lungs - battled chest
Anxiety and panic attacks
What COPD stands for
Chronic obstructive pulmonary disease
Chronic bronchitis
Pathophysiology
- Airway inflamed - irritation
- Mucus production - due to 1.
- Causing narrowed airways
- Impaired ciliary
Cause of COPD
Smoking (90%)
Air pollution
Genetic
COPD
treatment/ management
Bronchodilators- relax muscle around airway to keep open
Antibiotics - infection
⬆️Oxygen
Airway clearance (postural drainage, percussion/ vibration)
Asthma
What is it
Chronic inflammatory disease
Airway OBSTRUCTION
Hyper reactive airways and bronchospasm
Asthma
What happenes
- Hyperactive airway that response to stimuli
- Airway tightens and narrows (inflammation and bronchospasm)
- Inflamed and increases goblet cells that creates excessive sputum which makes it more narrow and damaging tissue
- Causes wheezing and increases WOB
Asthma
Symptoms
⬆️WOB
Cough
Wheezing
SOB
⬇️gas exchange (Hypercapnia/ hypoxia)
Chronic changes
Thickening airway / narrow airway (bronchoconstriction)
Fibrosis (scaring)