Human Genetic Disorders

Question 0

______ traits are always expressed in a persons phenotype.

Answer 0

Dominant

Question 1

How many pairs of matching homologous chromosomes are there?

Answer 1

22

Question 2

Huntington’s disease is a _____ genetic disorder caused by a rare autosomal dominant allele (causes death)

Answer 2

Lethal

Question 3

Dominant allele on chromosome __ is the culprit for Huntington’s disease.

Answer 3

4

Question 4

Huntington’s disease is the deterioration of the ______ system, particularly the brain.

Answer 4

Nervous

Question 5

Huntington’s disease results in….

Answer 5

Uncontrolled, jerky movements of head and limbs

Question 6

Achondroplasia is a form of _______

Answer 6

Dwarfism

Question 7

Achondroplasia is inherited as an autosomal _______ disorder.

Answer 7

Dominant

Question 8

People who have achondroplasia have abnormally short ____ & ____ relative to other body parts.

Answer 8

Arms & legs

Question 9

People who see and write letters or parts of words backwards have….

Answer 9

Dyslexia

Question 10

Dyslexia is a ______ trait.

Answer 10

Dominant

Question 11

Most genetic disorders are caused by ______ alleles.

Answer 11

Recessive

Question 12

Cystic fibrosis is one of the most common _____ genetic disorders among Americans.

Answer 12

Lethal

Question 13

The gene for Cystic Fibrosis is located on chromosome __.

Answer 13

7

Question 14

In cystic fibrosis, mucus accumulates in the ________ tract and in lungs.

Answer 14

Digestive

Question 15

During Cystic fibrosis, breathing is difficult, thickened _____ slows secretion of digestive enzymes, so food can not be digested properly.

Answer 15

Mucus

Question 16

Treatments for Cystic fibrosis include….

Answer 16

Physical therapy, special diet, and new drug therapies

Question 17

Most common in black Americans whose families originated in Africa and white Americans whose families originated in countries surrounding the Mediterranean Sea.

Answer 17

Sickle cell anemia

Question 18

Sickle cell anemia is inherited as autosomal _____ trait.

Answer 18

Recessive

Question 19

Someone with Sickle cell has red blood cells that are shaped like a sickle (half moon) not _____.

Answer 19

Round

Question 20

The life span of sickle cells are _____.

Answer 20

Shorter

Question 21

Sickle cell anemia clogs small blood vessels causing _____ damage and deprivation of oxygen and nutrients.

Answer 21

Tissue

Question 22

Treatments for Sickle cell anemia include….

Answer 22

Blood transfusion and drug therapy

Question 23

Tay Sachs is an autosomal _____ disorder.

Answer 23

Recessive

Question 24

Tay Sachs affects the central ____ system.

Answer 24

Nervous

Question 25

Recessive alleles result in the absence of _____ that normally break down a _____ produced and stored in tissues of the central nervous system.

Answer 25

Enzymes, lipid

Question 26

In Tay Sachs, the lipid accumulates in the ____.

Answer 26

Brain

Question 27

Tay Sachs results in…

Answer 27

Blindness, loss of movement, and mental deterioration

Question 28

Symptoms of Tay Sachs begin within the __ year of life.

Answer 28

1st

Question 29

Tay Sachs results in death before age __.

Answer 29

5

Question 30

The allele in Tay Sachs is common among Pennsylvania Dutch people and the ____________ people.

Answer 30

Ashkenazi Jewish

Question 31

PKU is an abbreviation for…..

Answer 31

Phenylketonuria

Question 32

PKU results from the absence of enzymes that convert the amino acid, phenylketonuria, to ______.

Answer 32

Tyrosine

Question 33

PKU accumulates in the body and damages the _________ system.

Answer 33

Central nervous

Question 34

When are tests for PKU given?

Answer 34

At birth

Question 35

Infants affected by PKU are given a diet low in phenylalanine until ________.

Answer 35

Their brains are fully developed

Question 36

Which disorder means having no skin pigment?

Answer 36

Albinism

Question 37

_____ results in very pale skin and white-blonde hair.

Answer 37

Albinism

Question 38

Albinism affects ___ races.

Answer 38

All

Question 39

An X-linked inheritance is located on the _________.

Answer 39

Sex chromosomes

Question 40

Examples of an X-linked Inheritance disorder are…

Answer 40

Color blindness ; Hemophilia

Question 41

Color blindness is the inability to distinguish __________.

Answer 41

Among some or all colors

Question 42

In color blindness, mutant forms of the X-linked genes change the light-absorbing of sensory ______ inside the eyes.

Answer 42

Receptors

Question 43

Normally, humans can detect differences among ___ colors. One with red-green color blindness sees fewer than __ colors.

Answer 43

150, 25

Question 44

Hemophilia is a _____ clotting disorder.

Answer 44

Blood

Question 45

About 1 in ____ males are affected.

Answer 45

7,000

Question 46

Treatments for hemophilia include…

Answer 46

Plasma, gene cloning, Factor VIII drugs