Human flora Flashcards
what are commensals?
aerobic and anaerobic genera and species that do no harm to the host when confined to their proper site
What are:
Transients
Opportunists
Pathogens
T: Micro - organisms which reside for a short time (eg 1 day, 1 week) in a particular site, without damage to the host
O:incapable of invading or damaging normal host; capable of invading or damaging when immunity compromised
P:capable of invading or damaging normal host by toxigenic action or invasion, to cause disease
Examples of commensals of nose, mouth? Pathogens?
nose staph.aureus mouth: oralstreptococci neisseria anaerobic bacteria fungi
pathogens: strep.pneumoniae
neisseria
meningitidis
Commensals of large bowel?
bacteroides spp
clostridia
enterococci and e.coli (enterobacteria)
fungi
lactobacilli
helminths - protozoa
Commensals of female lower genital tract?
bacteroides spp
enterobacteria
fungi
lacobacilli
how can antibiotics cause Candidiasis?
Mouth: Antibiotics reduce normal flora and allow overgrowth of Candida albicans. This invades the mucosa to cause thrush.
4 factors leading to opportunistic infection
compromised immunity
antibiotics or normal flora loss
breach of physical barriers
impaired normal clearance mechanisms (e.g. smoking)